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Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response
DR Wang, XL Wu, YL Sun - Signal transduction and targeted therapy, 2022 - nature.com
Cancers are highly complex diseases that are characterized by not only the overgrowth of
malignant cells but also an altered immune response. The inhibition and reprogramming of …
malignant cells but also an altered immune response. The inhibition and reprogramming of …
Revolutionization in cancer therapeutics via targeting major immune checkpoints PD-1, PD-L1 and CTLA-4
Numerous research reports have witnessed dramatic advancements in cancer therapeutic
approaches through immunotherapy. Blocking immunological checkpoint pathways …
approaches through immunotherapy. Blocking immunological checkpoint pathways …
Therapeutic advances in non‐small cell lung cancer: Focus on clinical development of targeted therapy and immunotherapy
Y Cheng, T Zhang, Q Xu - MedComm, 2021 - Wiley Online Library
Lung cancer still contributes to nearly one‐quarter cancer‐related deaths in the past
decades, despite the rapid development of targeted therapy and immunotherapy in non …
decades, despite the rapid development of targeted therapy and immunotherapy in non …
[HTML][HTML] Evolving strategies and application of proteins and peptide therapeutics in cancer treatment
Several proteins and peptides have therapeutic potential and can be used for cancer
therapy. By binding to cell surface receptors and other indicators uniquely linked with or …
therapy. By binding to cell surface receptors and other indicators uniquely linked with or …
[HTML][HTML] Immune checkpoint inhibitors in non-small cell lung cancer: From current perspectives to future treatments—A systematic review
A Olivares-Hernández, EG Del Portillo… - Annals of …, 2023 - ncbi.nlm.nih.gov
Background The introduction of immunotherapy in the treatment of non-small cell lung
cancer (NSCLC) has resulted in a radical change in patients' treatment responses and …
cancer (NSCLC) has resulted in a radical change in patients' treatment responses and …
NSCLC: from tumorigenesis, immune checkpoint misuse to current and future targeted therapy
L Raskova Kafkova, JM Mierzwicka… - Frontiers in …, 2024 - frontiersin.org
Non-small cell lung cancer (NSCLC) is largely promoted by a multistep tumorigenesis
process involving various genetic and epigenetic alterations, which essentially contribute to …
process involving various genetic and epigenetic alterations, which essentially contribute to …
Emerging therapeutic strategies for enhancing sensitivity and countering resistance to programmed cell death protein 1 or programmed death‐ligand 1 inhibitors in …
LC Villaruz, GR Blumenschein Jr, GA Otterson… - Cancer, 2023 - Wiley Online Library
The availability of agents targeting the programmed cell death protein 1 (PD‐1)/programmed
death‐ligand 1 (PD‐L1) immune checkpoint has transformed treatment of advanced and/or …
death‐ligand 1 (PD‐L1) immune checkpoint has transformed treatment of advanced and/or …
Crosstalk between cGAS-STING pathway and autophagy in cancer immunity
Q Lu, Y Chen, J Li, F Zhu, Z Zheng - Frontiers in Immunology, 2023 - frontiersin.org
The cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway is
critical in cancer immunity. Autophagy is a highly conserved process that is responsible for …
critical in cancer immunity. Autophagy is a highly conserved process that is responsible for …
CD33 expression on peripheral blood monocytes predicts efficacy of anti-PD-1 immunotherapy against non-small cell lung cancer
Non-small cell lung carcinoma (NSCLC) is the leading cause of cancer-related deaths
globally. Immune checkpoint blockade (ICB) has transformed cancer medicine, with anti …
globally. Immune checkpoint blockade (ICB) has transformed cancer medicine, with anti …
Systems biology strategy and experimental validation to uncover the pharmacological mechanism of **huang Pill in treating non-small cell lung cancer
Z Zhuang, D Huang, ZR Sheng, ZJ Ye, H Jiang, Y Yuan… - Phytomedicine, 2023 - Elsevier
Background Non-small cell lung cancer (NSCLC) accounts for almost 85% of lung cancer-
related deaths worldwide. **huang Pill (XHP) is a representative anticancer Chinese …
related deaths worldwide. **huang Pill (XHP) is a representative anticancer Chinese …