Ene‐reductase: a multifaceted biocatalyst in organic synthesis

T Kumar Roy, R Sreedharan, P Ghosh… - … A European Journal, 2022 - Wiley Online Library
Biocatalysis integrate microbiologists, enzymologists, and organic chemists to access the
repertoire of pharmaceutical and agrochemicals with high chemoselectivity, regioselectivity …

Enzymatic strategies for asymmetric synthesis

M Hall - RSC Chemical Biology, 2021 - pubs.rsc.org
Enzymes, at the turn of the 21st century, are gaining a momentum. Especially in the field of
synthetic organic chemistry, a broad variety of biocatalysts are being applied in an …

Ene-reductase transformation of massoia lactone to δ-decalactone in a continuous-flow reactor

E Szczepańska, D Colombo, F Tentori, T Olejniczak… - Scientific Reports, 2021 - nature.com
The demand for natural food flavorings increases every year. Biotransformation has become
an attractive approach to obtain natural products. In this work, enantiomerically pure (R)-(+) …

Immobilization of Coupled Enzymes onto Metalated Hierarchical Organic Microspheres

Y Li, W Wang, Y Sun, J Fan, H Zhang… - ACS Applied Materials & …, 2024 - ACS Publications
Hierarchical organic microspheres (HOMs) have emerged as an ideal carrier for
immobilizing biomacromolecules. In this research, an in-depth investigation into the …

Biocatalytic reduction of alkenes in micro-aqueous organic solvent catalysed by an immobilised ene reductase

R Villa, C Ferrer-Carbonell, CE Paul - Catalysis Science & Technology, 2023 - pubs.rsc.org
Biocatalytic asymmetric reduction of alkenes in organic solvent is attractive for enantiopurity
and product isolation, yet remains under developed. Herein we demonstrate the robustness …

Design and application of a bi-functional redox biocatalyst through covalent co-immobilization of ene-reductase and glucose dehydrogenase

F Nagy, I Gyujto, G Tasnádi, B Barna… - Journal of …, 2020 - Elsevier
An immobilized bi-functional redox biocatalyst was designed for the asymmetric reduction of
alkenes by nicotinamide-dependent ene-reductases. The biocatalyst, which consists of co …

Selective ene‐reductase immobilization to magnetic nanoparticles through a novel affinity tag

AA Zanker, N Ahmad, TH Son… - Biotechnology …, 2021 - Wiley Online Library
Abstract Background Magnetic nanoparticles (MNPs) are becoming more important as
carriers, because of their large specific surface area and easy separability. They are …

[HTML][HTML] Influence of carrier structure and physicochemical factors on immobilisation of fungal laccase in terms of Bisphenol a removal

K Wlizło, J Polak, J Kapral-Piotrowska, M Grąz… - Catalysts, 2020 - mdpi.com
Laccase from Pleurotus ostreatus was immobilised on porous Purolite® carriers and amino-
functionalised ultrafiltration membranes. The results indicated a correlation between the …

Immobilised Alcohol Dehydrogenase and Ene‐Reductase Work in Concert to Reduce Cyclohex‐2‐enone in Bulk Organic Solvent

A Pintor, A Volkov, I Lavandera… - …, 2024 - Wiley Online Library
Enone reduction by ene‐reductase (ERED) has not been reported yet in bulk organic media
probably due to expected challenges with the cofactor recycling using a second enzyme and …

Advances and Challenges in the Development of Immobilized Enzymes for Batch and Flow Biocatalyzed Processes

S Patti, I Magrini Alunno, S Pedroni, S Riva… - …, 2024 - Wiley Online Library
The development of immobilized enzymes both for batch and continuous flow biocatalytic
processes has gained significant traction in recent years, driven by the need for cost …