Sex differences in intestinal carbohydrate metabolism promote food intake and sperm maturation

B Hudry, E de Goeij, A Mineo, P Gaspar… - Cell, 2019 - cell.com
Physiology and metabolism are often sexually dimorphic, but the underlying mechanisms
remain incompletely understood. Here, we use the intestine of Drosophila melanogaster to …

Intraspecific variation of heat tolerance in a model ectotherm: The role of oxygen, cell size and body size

FP Leiva, M Santos, EL Rezende… - Functional …, 2024 - Wiley Online Library
Virtually all aspects of the biology of ectotherms are size‐and temperature‐dependent.
Aerobic metabolism is often proposed to explain such relationships, with oxygen limitation …

Flies developed small bodies and small cells in warm and in thermally fluctuating environments

M Czarnoleski, BS Cooper, J Kierat… - Journal of …, 2013 - journals.biologists.com
Although plasma membranes benefit cells by regulating the flux of materials to and from the
environment, these membranes cost energy to maintain. Because smaller cells provide …

Systematic perturbation of cytoskeletal function reveals a linear scaling relationship between cell geometry and fitness

RD Monds, TK Lee, A Colavin, T Ursell, S Quan… - Cell reports, 2014 - cell.com
Diversification of cell size is hypothesized to have occurred through a process of
evolutionary optimization, but direct demonstrations of causal relationships between cell …

Cell size, body size and Peto's paradox

S Maciak - BMC Ecology and Evolution, 2022 - Springer
Carcinogenesis is one of the leading health concerns afflicting presumably every single
animal species, including humans. Currently, cancer research expands considerably …

Cellular sex throughout the organism underlies somatic sexual differentiation

C Hérault, T Pihl, B Hudry - Nature Communications, 2024 - nature.com
Sex chromosomes underlie the development of male or female sex organs across species.
While systemic signals derived from sex organs prominently contribute to sex-linked …

Predictability rather than amplitude of temperature fluctuations determines stress resistance in a natural population of Drosophila simulans

T Manenti, JG Sørensen, NN Moghadam… - Journal of …, 2014 - academic.oup.com
The adaptability of organisms to novel environmental conditions depends on the amount of
genetic variance present in the population as well as on the ability of individuals to adjust …

Genome-Wide Analysis Reveals Novel Regulators of Growth in Drosophila melanogaster

SC Vonesch, D Lamparter, TFC Mackay… - PLoS …, 2016 - journals.plos.org
Organismal size depends on the interplay between genetic and environmental factors.
Genome-wide association (GWA) analyses in humans have implied many genes in the …

Developmental Stability: A Major Role for Cyclin G in Drosophila melanogaster

V Debat, S Bloyer, F Faradji, N Gidaszewski… - PLoS …, 2011 - journals.plos.org
Morphological consistency in metazoans is remarkable given the pervasive occurrence of
genetic variation, environmental effects, and developmental noise. Developmental stability …

Parallel trait adaptation across opposing thermal environments in experimental Drosophila melanogaster populations

R Tobler, J Hermisson, C Schlötterer - Evolution, 2015 - academic.oup.com
Thermal stress is a pervasive selective agent in natural populations that impacts organismal
growth, survival, and reproduction. Drosophila melanogaster exhibits a variety of putatively …