[HTML][HTML] Renal tubule injury: a driving force toward chronic kidney disease

BC Liu, TT Tang, LL Lv, HY Lan - Kidney international, 2018 - Elsevier
Renal tubules are the major component of the kidney and are vulnerable to a variety of
injuries including hypoxia, proteinuria, toxins, metabolic disorders, and senescence. It has …

Danger signals in stroke and their role on microglia activation after ischemia

E Gülke, M Gelderblom… - Therapeutic advances in …, 2018 - journals.sagepub.com
Ischemic stroke is a major cause of death. Besides the direct damage resulting from oxygen
and glucose deprivation, sterile inflammation plays a pivotal role in increasing cellular …
JJ Volpe, HC Kinney, FE Jensen… - International Journal of …, 2011 - Elsevier
Brain injury in the premature infant, a problem of enormous importance, is associated with a
high risk of neurodevelopmental disability. The major type of injury involves cerebral white …

Mediators of inflammation in acute kidney injury

A Akcay, Q Nguyen, CL Edelstein - Mediators of inflammation, 2009 - Wiley Online Library
Acute kidney injury (AKI) remains to be an independent risk factor for mortality and morbidity.
Inflammation is now believed to play a major role in the pathopathophysiology of AKI. It is …

NASH is an inflammatory disorder: pathogenic, prognostic and therapeutic implications

GC Farrell, D Van Rooyen, L Gan, S Chitturi - Gut and liver, 2012 - pmc.ncbi.nlm.nih.gov
While non-alcoholic fatty liver disease (NAFLD) is highly prevalent (15% to 45%) in modern
societies, only 10% to 25% of cases develop hepatic fibrosis leading to cirrhosis, end-stage …