Background Despite advances in early detection and therapies, cancer is still one of the
most common causes of death worldwide. Since each tumor is unique, there is a need to …

Cellular communication can be mediated by the exchange of biological information, mainly
in the form of proteins and RNAs. This can occur when extracellular vesicles, such as …

Rho GTPases are a family of small G proteins that regulate a wide array of cellular
processes related to their key roles controlling the cytoskeleton. Cancer is a multistep …

Extracellular vesicles are a heterogeneous group of cell-derived membranous structures
comprising exosomes and microvesicles, which originate from the endosomal system or …

Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …

The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

Cells from all three domains of life, Archaea, Bacteria and Eukarya, produce extracellular
vesicles (EVs) which are sometimes associated with filamentous structures known as …

While various clinical applications especially in oncology are now in progress such as
diagnosis, prognosis, therapy monitoring, or patient follow-up, the determination of structural …

The ability of cells to transmit bioactive molecules to recipient cells and the extracellular
environment is a fundamental requirement for both normal physiology and disease …

Long-and short-distance communication can take multiple forms. Among them are
exosomes and ectosomes, extracellular vesicles (EVs) released from the cell to deliver …