Pharmacogenomics: Biomarker directed therapy for bladder cancer
The clinical management of bladder cancer has seen little change over the last three
decades and there is pressing need to identify more effective treatments for advanced …
decades and there is pressing need to identify more effective treatments for advanced …
Immune-based therapies in penile cancer
VB Joshi, PE Spiess, A Necchi, CA Pettaway… - Nature Reviews …, 2022 - nature.com
Penile cancer is a rare genitourinary malignancy that is associated with poor outcomes and
severely limited therapeutic options that are generally non-curative when used to treat …
severely limited therapeutic options that are generally non-curative when used to treat …
Effective combinatorial immunotherapy for penile squamous cell carcinoma
Penile squamous cell carcinoma (PSCC) accounts for over 95% of penile malignancies and
causes significant mortality and morbidity in develo** countries. Molecular mechanisms …
causes significant mortality and morbidity in develo** countries. Molecular mechanisms …
Understanding genomics and the immune environment of penile cancer to improve therapy
The incidence of penile squamous cell carcinoma (PSCC) has increased in developed
countries over the past decades owing to increased human papilloma virus (HPV) exposure …
countries over the past decades owing to increased human papilloma virus (HPV) exposure …
[HTML][HTML] Relationship between human papillomavirus and penile cancer—implications for prevention and treatment
LC Kidd, S Chaing, J Chipollini… - Translational …, 2017 - ncbi.nlm.nih.gov
Penile cancer is a rare disease in the United States, but rates are increasing, causing
concern. Several risk factors have been associated with the disease, including human …
concern. Several risk factors have been associated with the disease, including human …
[HTML][HTML] The role of Her-2 in penile squamous cell carcinoma progression and cisplatin chemoresistance and potential for antibody-drug conjugate-based therapy
X Tan, Y Wang, Z Wu, Q Zhou, Y Tang, Z Liu… - European Journal of …, 2023 - Elsevier
Background Cisplatin-based chemotherapy has been the first choice for advanced penile
squamous cell carcinoma (PSCC) in the last decade, but its utility is limited by the low …
squamous cell carcinoma (PSCC) in the last decade, but its utility is limited by the low …
Methylation in HOX Clusters and Its Applications in Cancer Therapy
HOX genes are commonly known for their role in embryonic development, defining the
positional identity of most structures along the anterior–posterior axis. In postembryonic life …
positional identity of most structures along the anterior–posterior axis. In postembryonic life …
MEIS transcription factors in development and disease
D Schulte, D Geerts - Development, 2019 - journals.biologists.com
ABSTRACT MEIS transcription factors are key regulators of embryonic development and
cancer. Research on MEIS genes in the embryo and in stem cell systems has revealed …
cancer. Research on MEIS genes in the embryo and in stem cell systems has revealed …
[HTML][HTML] An analysis of nectin-4 (PVRL4) in penile squamous cell carcinoma
Penile squamous cell carcinoma (PSCC) remains a worldwide healthcare concern with poor
outcomes and inadequate therapeutic options. Molecular characterization continues to …
outcomes and inadequate therapeutic options. Molecular characterization continues to …
Genetics and penile cancer: recent developments and implications
Genetics and penile cancer: recent developments and implicat... : Current Opinion in Urology
Genetics and penile cancer: recent developments and implications : Current Opinion in …
Genetics and penile cancer: recent developments and implications : Current Opinion in …