Although mitochondria are best known for being the eukaryotic cell powerhouses, these
organelles participate in various cellular functions besides ATP production, such as calcium …

BACKGROUND The best-known role of spermatozoa is to fertilize the oocyte and to transmit
the paternal genome to offspring. These highly specialized cells have a unique structure …

Simple Summary Mitochondria play a crucial role in numerous cellular processes, including
energy production, apoptosis, and calcium homeostasis. In the male reproductive system …

During early development, apoptosis plays a major role in the ontogeny of the germ line as a
means of regulating the germ cell: Sertoli cell ratio. In the adult, apoptosis fulfils another …

At least 50% of infertile couple's problems are related to male factor infertility. This
Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial conducted in Urology unit of …

Macroautophagy (hereafter autophagy) is an evolutionarily highly conserved cellular
process that participates in the maintenance of intracellular homeostasis through the …

ABSTRACT STUDY QUESTION In addition to sperm motility, which major biological
characteristics of sperm fertility potential are associated with mitochondrial functionality …

Objective To evaluate whether DNA fragmentation and/or mitochondrial membrane potential
(MMP) predict natural conception better than standard sperm parameters. Design …

STUDY QUESTION Are all components of the peroxiredoxins (PRDXs) system important to
control the levels of reactive oxygen species (ROS) to maintain viability and DNA integrity in …

STUDY QUESTION Does mitochondrial permeability transition (MPT) induced by calcium
overload cause reactive oxygen species (ROS) production and DNA fragmentation in …