Millions of people visit high-altitude regions annually and more than 80 million live
permanently above 2,500 m. Acute high-altitude exposure can trigger high-altitude illnesses …

Several diseases associated with high-altitude exposure affect unacclimated individuals.
These diseases include acute mountain sickness (AMS), high-altitude cerebral edema …

Hypoxia is a state of reduced oxygen supply and excessive oxygen consumption. According
to the duration of hypoxic period, it can be classified as acute and chronic hypoxia. Both …

Long-term high altitudes (HA) exposure's impact on cognition has yielded inconsistent
findings in previous research. To address this, we conducted a meta-analysis of 49 studies …

Cognitive function is affected by low pressure and hypoxia in high-altitude environments,
and is regulated by altitude and exposure time. With the economic development in the …

Erythrocytosis, or increased production of red blood cells, is one of the most well-
documented physiological traits that varies within and among in high-altitude populations …

Depression is a mood disorder characterized by abnormal thoughts. The pathophysiology of
depression is related to the deficiency of serotonin (5HT), which is derived from tryptophan …

Cordyceps, also known as “zombie fungus”, is a non-poisonous mushroom that parasitizes
insects for growth and development by manipulating the host system in a way that makes the …

Curculigoside (CUR) is the main active component of traditional Chinese medicine
Curculigoorchioides Gaertn (**anmao in Chinese), which exhibits a variety of …

Acute moderate intensity exercise has been shown to improve cognitive performance. In
contrast, hypoxia is believed to impair cognitive performance. The detrimental effects of …