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Oxidative stress and the pathophysiology and symptom profile of schizophrenia spectrum disorders
Schizophrenia is associated with increased levels of oxidative stress, as reflected by an
increase in the concentrations of damaging reactive species and a reduction in anti-oxidant …
increase in the concentrations of damaging reactive species and a reduction in anti-oxidant …
Anti-inflammatory effects of 2nd generation antipsychotics in patients with schizophrenia: A systematic review and meta-analysis
Background Schizophrenia is a major psychiatric disorder with unknown aetiology. Recent
evidence suggests a potential role for cytokines in its pathophysiology and that antipsychotic …
evidence suggests a potential role for cytokines in its pathophysiology and that antipsychotic …
Blood–brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders
M Fiorentino, A Sapone, S Senger, SS Camhi… - Molecular autism, 2016 - Springer
Background Autism spectrum disorders (ASD) are complex conditions whose pathogenesis
may be attributed to gene–environment interactions. There are no definitive mechanisms …
may be attributed to gene–environment interactions. There are no definitive mechanisms …
Neuropharmacological effect of risperidone: From chemistry to medicine
As the second-oldest atypical antipsychotic, risperidone has a long history of off-label usage
for treating behavioural and psychological signs and symptoms of dementia (BPSD), such …
for treating behavioural and psychological signs and symptoms of dementia (BPSD), such …
Prevalence and clinical characteristics of serum neuronal cell surface antibodies in first-episode psychosis: a case-control study
Background Psychosis is a common presenting feature in antibody-mediated encephalitis,
for which prompt recognition and treatment usually leads to remission. We aimed to …
for which prompt recognition and treatment usually leads to remission. We aimed to …
Inflammation in schizophrenia: a question of balance
In the past decade, there has been renewed interest in immune/inflammatory changes and
their associated oxidative/nitrosative consequences as key pathophysiological mechanisms …
their associated oxidative/nitrosative consequences as key pathophysiological mechanisms …
Minocycline and antipsychotics inhibit inflammatory responses in BV-2 microglia activated by LPS via regulating the MAPKs/JAK-STAT signaling pathway
Y Long, Y Wang, Y Shen, J Huang, Y Li, R Wu, J Zhao - BMC psychiatry, 2023 - Springer
Background Abnormal activation of microglia is involved in the pathogenesis of
schizophrenia. Minocycline and antipsychotics have been reported to be effective in …
schizophrenia. Minocycline and antipsychotics have been reported to be effective in …
Immune abnormalities in autism spectrum disorder—could they hold promise for causative treatment?
D Gładysz, A Krzywdzińska, KK Hozyasz - Molecular neurobiology, 2018 - Springer
Autism spectrum disorders (ASD) are characterized by impairments in language and
communication development, social behavior, and the occurrence of stereotypic patterns of …
communication development, social behavior, and the occurrence of stereotypic patterns of …
Antioxidant properties of second-generation antipsychotics: Focus on microglia
Recent studies suggest a primary role of oxidative stress in an early phase of the
pathogenesis of schizophrenia and a strong neurobiological link has been found between …
pathogenesis of schizophrenia and a strong neurobiological link has been found between …
Effects of risperidone on cytokine profile in drug-naïve first-episode psychosis
Background: There is robust evidence that schizophrenia is characterized by immune-
inflammatory abnormalities, including variations on cytokine levels. The results of previous …
inflammatory abnormalities, including variations on cytokine levels. The results of previous …