Systemic inflammation after stroke: implications for post‐stroke comorbidities
Immunological mechanisms have come into the focus of current translational stroke
research, and the modulation of neuroinflammatory pathways has been identified as a …
research, and the modulation of neuroinflammatory pathways has been identified as a …
Immune pathways in etiology, acute phase, and chronic sequelae of ischemic stroke
Inflammation and immune mechanisms are crucially involved in the pathophysiology of the
development, acute damage cascades, and chronic course after ischemic stroke …
development, acute damage cascades, and chronic course after ischemic stroke …
Infection as a stroke risk factor and determinant of outcome after stroke
Understanding the relationship between infection and stroke has taken on new urgency in
the era of the coronavirus disease 2019 (COVID-19) pandemic. This association is not a …
the era of the coronavirus disease 2019 (COVID-19) pandemic. This association is not a …
Immunodepression, infections, and functional outcome in ischemic stroke
Stroke remains one of the main causes of mortality and morbidity worldwide. Immediately
after stroke, a neuroinflammatory process starts in the brain, triggering a systemic …
after stroke, a neuroinflammatory process starts in the brain, triggering a systemic …
The immunology of acute stroke
Recent clinical and experimental studies have highlighted a complex role for the immune
system in the pathophysiological changes that occur after acute stroke. Sensors of the innate …
system in the pathophysiological changes that occur after acute stroke. Sensors of the innate …
Targeting the immune system for ischemic stroke
Stroke is responsible for almost 6 million deaths and more than 10% of all mortalities each
year, and two-thirds of stroke survivors remain disabled. With treatments for ischemic stroke …
year, and two-thirds of stroke survivors remain disabled. With treatments for ischemic stroke …
Stroke and the immune system: from pathophysiology to new therapeutic strategies
R Macrez, C Ali, O Toutirais, B Le Mauff… - The Lancet …, 2011 - thelancet.com
Stroke is the second most common cause of death worldwide and a major cause of acquired
disability in adults. Despite tremendous progress in understanding the pathophysiology of …
disability in adults. Despite tremendous progress in understanding the pathophysiology of …
DAMP signaling is a key pathway inducing immune modulation after brain injury
Acute brain lesions induce profound alterations of the peripheral immune response
comprising the opposing phenomena of early immune activation and subsequent …
comprising the opposing phenomena of early immune activation and subsequent …
New horizons for newborn brain protection: enhancing endogenous neuroprotection
KJ Hassell, M Ezzati, D Alonso-Alconada… - Archives of Disease in …, 2015 - fn.bmj.com
Intrapartum-related events are the third leading cause of childhood mortality worldwide and
result in one million neurodisabled survivors each year. Infants exposed to a perinatal insult …
result in one million neurodisabled survivors each year. Infants exposed to a perinatal insult …
Stroke-induced immunodepression and dysphagia independently predict stroke-associated pneumonia–The PREDICT study
S Hoffmann, H Harms, L Ulm… - Journal of Cerebral …, 2017 - journals.sagepub.com
Stroke-associated pneumonia is a frequent complication after stroke associated with poor
outcome. Dysphagia is a known risk factor for stroke-associated pneumonia but …
outcome. Dysphagia is a known risk factor for stroke-associated pneumonia but …