Automation empowers self-sustainable adaptive processes and personalized services in
many industries. The implementation of the integrated healthcare paradigm built on Health …

Over the past decade, there has been an unprecedented international focus on improved
quality and availability of medical care, which has reignited interest in clinical automation …

In this paper, a model predictive control system for the depth of hypnosis is proposed and
analyzed. This approach considers simultaneous co-administration of the hypnotic and …

Objective The main objective of this research is the design and implementation of a new
fuzzy logic tool for automatic drug delivery in patients undergoing general anesthesia. The …

In this paper we present the preliminary clinical results obtained with a PID control scheme
for propofol and remifentanil coadministration during general anesthesia. The bispectral …

In this paper we propose a methodology for a patient-individualized tuning of the parameters
of a proportional–integral–derivative (PID) controller that regulates the depth of hypnosis in …

Fractional calculus has been opening new doors in terms of better modeling and control of
several phenomena and processes. Biomedical engineering has seen a lot of combined …

Abstract Background and Objective: Many methodologies have been proposed for the
control of total intravenous anesthesia in general surgery, as this yields a reduced stress for …

During general anesthesia, anesthesiologists adjust the level of hypnosis based on dose
regimes given by drug manufacturers and their own observation. Thus, their actions are …

In this paper we present a new model predictive control system for the depth of hypnosis in
general anesthesia. The depth of hypnosis is measured by the Bispectral Index Scale signal …