An estimated 20–25% of the population is affected by chronic, non-communicable
inflammatory skin diseases. Chronic skin inflammation has many causes. Among the most …

Bullous pemphigoid (BP) is the most common type of subepidermal autoimmune bullous
diseases. BP characteristically affects the elderly and is seen mainly in patients older than …

Autoimmune bullous disorders are a heterogeneous spectrum of skin disorders
characterized by the production of autoantibodies against adhesion molecules of the skin …

There are several lines of evidence indicating that the physiopathological bases of bullous
pemphigoid (BP), the most common subepidermal autoimmune bullous disease, are …

Epidermolysis bullosa acquisita (EBA) is an orphan autoimmune disease. Patients with EBA
suffer from chronic inflammation as well as blistering and scarring of the skin and mucous …

Paraneoplastic pemphigus (PNP) is a rare but life-threatening mucocutaneous disease
mediated by paraneoplastic autoimmunity. Various neoplasms are associated with PNP …

Pemphigus vulgaris (PV) and bullous pemphigoid (BP) are autoantibody-mediated diseases
clinically characterized by blisters and erosions of skin and/or mucous membranes. Immune …

Regulatory T (Treg) cells play a key role in maintaining immune tolerance and tissue
homeostasis. However, in some disease microenvironments, Treg cells exhibit fragility …

Bullous pemphigoid (BP) is the most common autoimmune bullous disease, characterized
by severe pruritus and skin blistering. The loss of tolerance against Collagen XVII, also …

Autoimmune bullous skin diseases, such as pemphigus and pemphigoid, may enable
clarification of the mechanisms of immune regulation in the skin. Pemphigus and …