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[HTML][HTML] Phage therapy—challenges, opportunities and future prospects
B Zalewska-Piątek - Pharmaceuticals, 2023 - mdpi.com
The increasing drug resistance of bacteria to commonly used antibiotics creates the need to
search for and develop alternative forms of treatment. Phage therapy fits this trend perfectly …
search for and develop alternative forms of treatment. Phage therapy fits this trend perfectly …
Drug delivery strategies for antibiofilm therapy
Although new antibiofilm agents have been developed to prevent and eliminate pathogenic
biofilms, their widespread clinical use is hindered by poor biocompatibility and …
biofilms, their widespread clinical use is hindered by poor biocompatibility and …
Protein cages: from fundamentals to advanced applications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …
[HTML][HTML] Formulation, stabilisation and encapsulation of bacteriophage for phage therapy
Against a backdrop of global antibiotic resistance and increasing awareness of the
importance of the human microbiota, there has been resurgent interest in the potential use of …
importance of the human microbiota, there has been resurgent interest in the potential use of …
Phage therapy: What factors shape phage pharmacokinetics and bioavailability? Systematic and critical review
K Dąbrowska - Medicinal research reviews, 2019 - Wiley Online Library
Bacteriophages are not forgotten viruses anymore: scientists and practitioners seek to
understand phage pharmacokinetics in animals and humans, investigating bacteriophages …
understand phage pharmacokinetics in animals and humans, investigating bacteriophages …
Engineered CRISPR-Cas systems for the detection and control of antibiotic-resistant infections
Antibiotic resistance is spreading rapidly around the world and seriously impeding efforts to
control microbial infections. Although nucleic acid testing is widely deployed for the …
control microbial infections. Although nucleic acid testing is widely deployed for the …
Microencapsulation for pharmaceutical applications: a review
C Yan, SR Kim - ACS applied bio materials, 2024 - ACS Publications
In order to improve bioavailability, stability, control release, and target delivery of active
pharmaceutical ingredients (APIs), as well as to mask their bitter taste, to increase their …
pharmaceutical ingredients (APIs), as well as to mask their bitter taste, to increase their …
Gram-positive bacterial extracellular vesicles and their impact on health and disease
During recent years it has become increasingly clear that the release of extracellular
vesicles (EVs) is a feature inherent to all cellular life forms. These lipid bilayer-enclosed …
vesicles (EVs) is a feature inherent to all cellular life forms. These lipid bilayer-enclosed …
[HTML][HTML] Recent advances in bacteriophage-based therapeutics: Insight into the post-antibiotic era
H Ling, X Lou, Q Luo, Z He, M Sun, J Sun - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Antibiotic resistance is one of the biggest threats to global health, as it can make the
treatment of bacterial infections in humans difficult owing to their high incidence rate …
treatment of bacterial infections in humans difficult owing to their high incidence rate …
Pharmacologically aware phage therapy: pharmacodynamic and pharmacokinetic obstacles to phage antibacterial action in animal and human bodies
The use of viruses infecting bacteria (bacteriophages or phages) to treat bacterial infections
has been ongoing clinically for approximately 100 years. Despite that long history, the …
has been ongoing clinically for approximately 100 years. Despite that long history, the …