An update on the management of childhood-onset systemic lupus erythematosus

VC Trindade, M Carneiro-Sampaio, E Bonfa, CA Silva - Pediatric Drugs, 2021 - Springer
Childhood-onset systemic lupus erythematosus (cSLE) is a prototype of a multisystemic,
inflammatory, heterogeneous autoimmune condition. This disease is characterized by …

Systemic lupus erythematosus in children and young people

A Charras, E Smith, CM Hedrich - Current rheumatology reports, 2021 - Springer
Abstract Purpose of Review Juvenile-onset systemic lupus erythematosus ((j) SLE) is an
autoimmune/inflammatory disease that results in significant damage and disability. When …

Influence of X chromosome in sex-biased autoimmune diseases

CH Miquel, B Faz-Lopez, JC Guéry - Journal of autoimmunity, 2023 - Elsevier
Females have better ability to resolve infections, compared to males, but also, a greater
susceptibility to develop autoimmunity. Besides the initial interest on the contribution of sex …

Clinical and laboratory phenotypes in juvenile-onset Systemic Lupus Erythematosus across ethnicities in the UK

JS Massias, EMD Smith, E Al-Abadi, K Armon… - Lupus, 2021 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is a systemic autoimmune/inflammatory disease.
Patients diagnosed with juvenile-onset SLE (jSLE), when compared to individuals with adult …

Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus (jSLE)

V Natoli, A Charras, G Hahn, CM Hedrich - Molecular and Cellular …, 2023 - Springer
Systemic lupus erythematosus (SLE) is a rare autoimmune/inflammatory disease with
significant morbidity and mortality. Approximately 15–20% of SLE patients develop the …

Using a multi-institutional pediatric learning health system to identify systemic lupus erythematosus and lupus nephritis: development and validation of computable …

SE Wenderfer, JC Chang, AG Davies… - Clinical Journal of the …, 2022 - journals.lww.com
Results Final algorithms consisted of both utilization and diagnostic criteria. For both,
utilization criteria included two or more in-person visits with nephrology or rheumatology …

Clinical and laboratorial outcome of different age-onset systemic lupus erythematosus patients in Jiangsu, China: a multicentre retrospective study

L Wen, Z Chen, Z **, W Pan, L Liu, M Wu, F Ding… - Scientific reports, 2022 - nature.com
Studies on clinical features of systemic lupus erythematosus among different age-onset
patients are lacking in China. This multicentre study aimed to systemically compare clinical …

Systemic lupus erythematosus–are children miniature adults?

T Alexander, CM Hedrich - Clinical Immunology, 2022 - Elsevier
Systemic lupus erythematosus (SLE) is a systemic autoimmune/inflammatory disease that
can affect any organ system and cause significant damage and organ failure. Disease-onset …

Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: Data from the UK Juvenile-onset systemic lupus erythematosus cohort study

T Giani, EMD Smith, E Al-Abadi, K Armon, K Bailey… - Lupus, 2021 - journals.sagepub.com
Introduction Juvenile-onset systemic lupus erythematosus (JSLE) is a rare autoimmune/
inflammatory disease with significant morbidity and mortality. Neuropsychiatric (NP) …

The influence of sex hormones and X chromosome in immune responses

N Anesi, CH Miquel, S Laffont, JC Guéry - Sex and Gender Differences in …, 2023 - Springer
Males and females differ in their susceptibility to develop autoimmunity and allergy but also
in their capacity to cope with infections and cancers. Cellular targets and molecular …