Role of cardiolipin in mitochondrial signaling pathways
J Dudek - Frontiers in cell and developmental biology, 2017 - frontiersin.org
The phospholipid cardiolipin (CL) is an essential constituent of mitochondrial membranes
and plays a role in many mitochondrial processes, including respiration and energy …
and plays a role in many mitochondrial processes, including respiration and energy …
OPA1 processing in cell death and disease–the long and short of it
The regulation of mitochondrial dynamics by the GTPase OPA1, which is located at the inner
mitochondrial membrane, is crucial for adapting mitochondrial function and preserving …
mitochondrial membrane, is crucial for adapting mitochondrial function and preserving …
Prohibitin 2 is an inner mitochondrial membrane mitophagy receptor
The removal of unwanted or damaged mitochondria by autophagy, a process called
mitophagy, is essential for key events in development, cellular homeostasis, tumor …
mitophagy, is essential for key events in development, cellular homeostasis, tumor …
Mechanisms and roles of mitophagy in neurodegenerative diseases
Y Wang, N Liu, B Lu - CNS neuroscience & therapeutics, 2019 - Wiley Online Library
Mitochondria are double‐membrane‐encircled organelles existing in most eukaryotic cells
and playing important roles in energy production, metabolism, Ca2+ buffering, and cell …
and playing important roles in energy production, metabolism, Ca2+ buffering, and cell …
Prohibitins: a critical role in mitochondrial functions and implication in diseases
A Signorile, G Sgaramella, F Bellomo, D De Rasmo - Cells, 2019 - mdpi.com
Prohibitin 1 (PHB1) and prohibitin 2 (PHB2) are proteins that are ubiquitously expressed,
and are present in the nucleus, cytosol, and mitochondria. Depending on the cellular …
and are present in the nucleus, cytosol, and mitochondria. Depending on the cellular …
Sha** the mitochondrial inner membrane in health and disease
L Colina‐Tenorio, P Horten, N Pfanner… - Journal of internal …, 2020 - Wiley Online Library
Mitochondria play central roles in cellular energetics, metabolism and signalling. Efficient
respiration, mitochondrial quality control, apoptosis and inheritance of mitochondrial DNA …
respiration, mitochondrial quality control, apoptosis and inheritance of mitochondrial DNA …
Non-classical ferroptosis inhibition by a small molecule targeting PHB2
W Yang, B Mu, J You, C Tian, H Bin, Z Xu… - Nature …, 2022 - nature.com
Ferroptosis is a new type of programmed cell death characterized by iron-dependent lipid
peroxidation. Ferroptosis inhibition is thought as a promising therapeutic strategy for a …
peroxidation. Ferroptosis inhibition is thought as a promising therapeutic strategy for a …
Alzheimer s disease and oxidative stress: a review
M Pohanka - Current medicinal chemistry, 2014 - ingentaconnect.com
Alzheimer´ s disease (AD) is a neurodegenerative disorder with no known cure and rapid
rise in incidence. The predominant cognitive impairment is currently treated using cognitive …
rise in incidence. The predominant cognitive impairment is currently treated using cognitive …
Multifaceted role of prohibitin in cell survival and apoptosis
YT Peng, P Chen, RY Ouyang, L Song - Apoptosis, 2015 - Springer
Human eukaryotic prohibitin (prohibitin-1 and prohibitin-2) is a membrane protein with
different cellular localizations. It is involved in multiple cellular functions, including energy …
different cellular localizations. It is involved in multiple cellular functions, including energy …
A cytosolic network suppressing mitochondria-mediated proteostatic stress and cell death
X Wang, XJ Chen - Nature, 2015 - nature.com
Mitochondria are multifunctional organelles whose dysfunction leads to neuromuscular
degeneration and ageing. The multi-functionality poses a great challenge for understanding …
degeneration and ageing. The multi-functionality poses a great challenge for understanding …