Glycoscience assembles all the scientific disciplines involved in studying various molecules
and macromolecules containing carbohydrates and complex glycans. Such an ensemble …

The Collaborative Computational Project No. 4 (CCP4) is a UK-led international collective
with a mission to develop, test, distribute and promote software for macromolecular …

The emergence of the betacoronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), represents a …

Coot is a tool widely used for model building, refinement, and validation of macromolecular
structures. It has been extensively used for crystallography and, more recently …

Vaccine efforts to combat the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), which is responsible for the current coronavirus disease 2019 (COVID-19) pandemic, are …

Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS)
coronaviruses (CoVs) are zoonotic pathogens with high fatality rates and pandemic …

Coronavirus spike proteins mediate receptor binding and membrane fusion, making them
prime targets for neutralizing antibodies. In the cases of severe acute respiratory syndrome …

Fast inhibitory neurotransmission in the brain is principally mediated by the neurotransmitter
GABA (γ-aminobutyric acid) and its synaptic target, the type A GABA receptor (GABAA …

Vaccine development against the SARS-CoV-2 virus focuses on the principal target of the
neutralizing immune response, the spike (S) glycoprotein. Adenovirus-vectored vaccines …

Multivalent presentation of viral glycoproteins can substantially increase the elicitation of
antigen-specific antibodies. To enable a new generation of anti-viral vaccines, we designed …