Insect cytochrome P450 monooxygenases (P450s) perform a variety of important
physiological functions, but it is their role in the detoxification of xenobiotics, such as natural …

Fungi have been extensively studied for their capacity to biotransform a wide range of
natural and xenobiotic compounds. This versatility is a reflection of the broad substrate …

Here, we provide mechanistic support for the involvement of the CYP9A subfamily of
cytochrome P450 monooxygenases in the detoxification of host plant defense compounds …

The regulatory process for assessing the risks of pesticides to bees relies heavily on the use
of the honeybee, Apis mellifera, as a model for other bee species. However, the validity of …

Cytochrome P450s play critical roles in the metabolic resistance of insecticides in insects.
Previous findings showed that enhanced P450 activity was an important mechanism …

Pharmaceuticals and personal care products (PPCPs) are often found in aquatic
environments. Microalgae-based bioremediation is cost-effective and ecologically friendly …

Honey bee (Apis mellifera) first-tier pesticide risk assessment is largely based on
standardized laboratory toxicity bioassays after both acute and chronic exposure. Recent …

Flupyradifurone, a novel butenolide insecticide, selectively targets insect nicotinic
acetylcholine receptors (nAChRs), comparable to structurally different insecticidal …

Metabolic alternation is a typical characteristic of insecticide resistance in insects. However,
mechanisms underlying metabolic alternation and how altered metabolism in turn affects …

Background Difference in physiology level between the immature and mature stages of
insects likely contribute to different mechanisms of insecticide resistance. It is well …