Optical microscopes are an important imaging tool that have effectively advanced the
development of modern biomedicine. In recent years, super-resolution microscopy (SRM) …

life science, clinical diagnostics, drug development, etc. Recent years have witnessed the
emergence of innovative analytical methods with high sensitivity and spatial-temporal …

We describe a technique based on secondary ion mass spectrometry with nanoprojectiles
(NP-SIMS) for determining the protein content of extracellular vesicles, EVs, via tagged …

Knowledge of the distributions of drugs, metabolites, and drug carriers within cells is a
prerequisite for the development of effective disease treatments. Intracellular component …

Cellular communication is vital for the survival of multicellular organisms. This process often
relies on a highly regulated mechanism called exocytosis, which involves the release of …

The cell is a heterogeneous chemical structure designed to accommodate its complex
cellular functions in a living organism. Quantitative chemical imaging at the cellular level …