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Cancer cachexia: molecular mechanisms and treatment strategies
Muscle wasting is a consequence of physiological changes or a pathology characterized by
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …
Neuromuscular junction transmission failure in aging and sarcopenia: The nexus of the neurological and muscular systems
Sarcopenia, or age-related decline in muscle form and function, exerts high personal,
societal, and economic burdens when untreated. Integrity and function of the neuromuscular …
societal, and economic burdens when untreated. Integrity and function of the neuromuscular …
Disruption of Neuromuscular Junction Following Spinal Cord Injury and Motor Neuron Diseases
C Nemeth, NL Banik, A Haque - International Journal of Molecular …, 2024 - mdpi.com
The neuromuscular junction (NMJ) is a crucial structure that connects the cholinergic motor
neurons to the muscle fibers and allows for muscle contraction and movement. Despite the …
neurons to the muscle fibers and allows for muscle contraction and movement. Despite the …
New intranasal and injectable gene therapy for healthy life extension
As the global elderly population grows, it is socioeconomically and medically critical to
provide diverse and effective means of mitigating the impact of aging on human health …
provide diverse and effective means of mitigating the impact of aging on human health …
Putting some muscle into sarcopenia—the pathogenesis, assessment and clinical impact of muscle loss in patients with inflammatory bowel disease
Background Sarcopenia, a loss of skeletal muscle mass or function, affects up to 50% of
patients with inflammatory bowel disease (IBD) and is associated with poor clinical …
patients with inflammatory bowel disease (IBD) and is associated with poor clinical …
Multimodal learning for map** genotype–phenotype dynamics
How complex phenotypes emerge from intricate gene expression patterns is a fundamental
question in biology. Integrating high-content genoty** approaches such as single-cell …
question in biology. Integrating high-content genoty** approaches such as single-cell …
Neuromuscular junction dysfunction in Lafora disease
Lafora disease (LD), a fatal neurodegenerative disorder, is caused by mutations in the
EPM2A gene encoding laforin phosphatase or NHLRC1 gene encoding malin ubiquitin …
EPM2A gene encoding laforin phosphatase or NHLRC1 gene encoding malin ubiquitin …
Effects of soy milk in conjunction with resistance training on physical performance and skeletal muscle regulatory markers in older men
N Bijeh, M Mohammadnia-Ahmadi… - Biological Research …, 2022 - journals.sagepub.com
Purpose: We aimed to determine the effects of 12 weeks of soy milk consumption combined
with resistance training (RT) on body composition, physical performance, and skeletal …
with resistance training (RT) on body composition, physical performance, and skeletal …
[HTML][HTML] Follistatin-respiratory connection predicting all-cause mortality among community-dwelling middle-to-old age individuals: Results from the I-Lan Longitudinal …
HC Shen, WJ Lee, CY Sun, WK Yu, WC Chen… - The Journal of nutrition …, 2024 - Elsevier
Objectives The link between aging and pulmonary function decline is well-established, but
the underlying mechanisms have yet to be fully revealed. Serum follistatin, a myokine …
the underlying mechanisms have yet to be fully revealed. Serum follistatin, a myokine …
The reign of follistatin in tumors and their microenvironment: implications for drug resistance
J Sosa, A Oyelakin, S Sinha - Biology, 2024 - mdpi.com
Simple Summary Within the extracellular milieu surrounding cancer cells exists an
ecosystem of heterogeneous cell populations that dictate tumor growth and survival via cell …
ecosystem of heterogeneous cell populations that dictate tumor growth and survival via cell …