Statistical challenges in longitudinal microbiome data analysis

S Kodikara, S Ellul, KA Lê Cao - Briefings in Bioinformatics, 2022 - academic.oup.com
The microbiome is a complex and dynamic community of microorganisms that co-exist
interdependently within an ecosystem, and interact with its host or environment. Longitudinal …

[HTML][HTML] Classifying spam emails using agglomerative hierarchical clustering and a topic-based approach

F Jáñez-Martino, R Alaiz-Rodríguez… - Applied Soft …, 2023 - Elsevier
Spam emails are unsolicited, annoying and sometimes harmful messages which may
contain malware, phishing or hoaxes. Unlike most studies that address the design of efficient …

Recurrent urinary tract infection and estrogen shape the taxonomic ecology and function of the postmenopausal urogenital microbiome

ML Neugent, A Kumar, NV Hulyalkar, KC Lutz… - Cell Reports …, 2022 - cell.com
Postmenopausal women are severely affected by recurrent urinary tract infection (rUTI). The
urogenital microbiome is a key component of the urinary environment. However, changes in …

Bayesian modeling of spatial molecular profiling data via Gaussian process

Q Li, M Zhang, Y **e, G **ao - Bioinformatics, 2021 - academic.oup.com
Motivation The location, timing and abundance of gene expression (both mRNA and
proteins) within a tissue define the molecular mechanisms of cell functions. Recent …

A Bayesian zero-inflated negative binomial regression model for the integrative analysis of microbiome data

S Jiang, G **ao, AY Koh, J Kim, Q Li, X Zhan - Biostatistics, 2021 - academic.oup.com
Microbiome omics approaches can reveal intriguing relationships between the human
microbiome and certain disease states. Along with identification of specific bacteria taxa …

Decision‐making support for the evaluation of clustering algorithms based on MCDM

W Wu, Z Xu, G Kou, Y Shi - Complexity, 2020 - Wiley Online Library
In many disciplines, the evaluation of algorithms for processing massive data is a
challenging research issue. However, different algorithms can produce different or even …

HARMONIES: a hybrid approach for microbiome networks inference via exploiting sparsity

S Jiang, G **ao, AY Koh, Y Chen, B Yao, Q Li… - Frontiers in …, 2020 - frontiersin.org
The human microbiome is a collection of microorganisms. They form complex communities
and collectively affect host health. Recently, the advances in next-generation sequencing …

Bayesian clustering of multiple zero-inflated outcomes

B Franzolini, A Cremaschi… - … of the Royal …, 2023 - royalsocietypublishing.org
Several applications involving counts present a large proportion of zeros (excess-of-zeros
data). A popular model for such data is the hurdle model, which explicitly models the …

A Bayesian semiparametric regression model for joint analysis of microbiome data

J Lee, M Sison-Mangus - Frontiers in microbiology, 2018 - frontiersin.org
The successional dynamics of microbial communities are influenced by the synergistic
interactions of physical and biological factors. In our motivating data, ocean microbiome …

An interpretable Bayesian clustering approach with feature selection for analyzing spatially resolved transcriptomics data

H Li, B Zhu, X Jiang, L Guo, Y **e, L Xu, Q Li - Biometrics, 2024 - academic.oup.com
Recent breakthroughs in spatially resolved transcriptomics (SRT) technologies have
enabled comprehensive molecular characterization at the spot or cellular level while …