[HTML][HTML] Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration

S Lyu, Z Dong, X Xu, HP Bei, HY Yuen, CWJ Cheung… - Bioactive materials, 2023 - Elsevier
Microneedle, as a novel drug delivery system, has attracted widespread attention due to its
non-invasiveness, painless and simple administration, controllable drug delivery, and …

Design principles of microneedles for drug delivery and sampling applications

Z Le, J Yu, YJ Quek, B Bai, X Li, Y Shou, B Myint, C Xu… - Materials Today, 2023 - Elsevier
Microneedles technology is a powerful platform to achieve efficient transdermal delivery of
bioactive molecules for local or systemic therapies attributing to their minimally invasive …

Multifunctional 3D‐printed pollen grain‐inspired hydrogel microrobots for on‐demand anchoring and cargo delivery

YW Lee, JK Kim, U Bozuyuk, NO Dogan… - Advanced …, 2023 - Wiley Online Library
While a majority of wireless microrobots have shown multi‐responsiveness to implement
complex biomedical functions, their functional executions are strongly dependent on the …

4D printing of a bioinspired microneedle array with backward‐facing barbs for enhanced tissue adhesion

D Han, RS Morde, S Mariani… - Advanced Functional …, 2020 - Wiley Online Library
Microneedle (MN), a miniaturized needle with a length‐scale of hundreds of micrometers,
has received a great deal of attention because of its minimally invasive, pain‐free, and easy …

Tannic acid–thioctic acid hydrogel: A novel injectable supramolecular adhesive gel for wound healing

C Chen, X Yang, S Li, C Zhang, Y Ma, Y Ma, P Gao… - Green …, 2021 - pubs.rsc.org
Skin tissue defects represent a major threat to human health. It is of vital importance for
researchers to develop novel ideal adhesives with strong adhesion, good biocompatibility …

Microneedles for transdermal diagnostics: Recent advances and new horizons

GS Liu, Y Kong, Y Wang, Y Luo, X Fan, X **e, BR Yang… - Biomaterials, 2020 - Elsevier
Point-of-care testing (POCT), defined as the test performed at or near a patient, has been
evolving into a complement to conventional laboratory diagnosis by continually providing …

Bioinspired microneedle patches: Biomimetic designs, fabrication, and biomedical applications

P Makvandi, A Maleki, M Shabani, ARJ Hutton… - Matter, 2022 - cell.com
Nature contains abundant systems that can significantly alter their structures and properties
to adapt to the surrounding environment. Through natural selection and unceasing …

A rapid corneal healing microneedle for efficient ocular drug delivery

H Shi, J Zhou, Y Wang, Y Zhu, D Lin, L Lei, S Vakal… - Small, 2022 - Wiley Online Library
Fungal keratitis (FK) remains a serious clinical problem worldwide, so the ultimate goal of
the treatment is to develop a minimally invasive, safe, and effective method for ocular drug …

Recent advances in oral and transdermal protein delivery systems

Y Yang, R Zhou, Y Wang, Y Zhang, J Yu… - Angewandte …, 2023 - Wiley Online Library
Protein and peptide drugs are predominantly administered by injection to achieve high
bioavailability, but this greatly compromises patient compliance. Oral and transdermal drug …

Oxygen releasing patches based on carbohydrate polymer and protein hydrogels for diabetic wound healing: A review

A Al Mamun, A Ullah, MEH Chowdhury… - International journal of …, 2023 - Elsevier
Diabetic wounds are among the major healthcare challenges, consuming billions of dollars
of resources and resulting in high numbers of morbidity and mortality every year. Lack of …