Several Dinophysis species produce diarrhoetic toxins (okadaic acid and dinophysistoxins)
and pectenotoxins, and cause gastointestinal illness, Diarrhetic Shellfish Poisoning (DSP) …

Protein phosphorylation plays a cardinal role in regulating many cellular processes in
eukaryotes. In particular, protein phosphorylation is a major currency of signal transduction …

The textbook of “Phytochemistry and bioactive compounds”, Volume 2 of the series—
Therapeutic use of Medicinal Plants and their Extracts, has been written to meet the needs of …

Protein phosphatase 2A (PP2A) comprises a family of serine/threonine phosphatases,
minimally containing a well conserved catalytic subunit, the activity of which is highly …

The cyclic heptapeptide, microcystin-LR, inhibits protein phosphatases 1 (PP1) and 2A
(PP2A) with K i, values below 0.1 nM. Protein phosphatase 2B is inhibited 1000-fold less …

Intrahepatic cholangiocarcinoma (ICC) is an aggressive bile duct malignancy that frequently
exhibits isocitrate dehydrogenase (IDH1/IDH2) mutations. Mutant IDH (IDHm) ICC is …

The beta-isoform of glycogen synthase kinase-3 (GSK3 beta) isolated from rabbit skeletal
muscle was inactivated 90-95% following incubation with MgATP and either MAP kinase …

Certain marine algae produce potent toxins that impact human health through the
consumption of contaminated shellfish and finfish and through water or aerosol exposure …

The reversible phosphorylation of proteins regulates almost all aspects of cell life, while
abnormal phosphorylation is a cause or consequence of many diseases. Mutations in …

While changes in gene expression are critical for many brain functions, including long-term
memory, little is known about the cellular processes that mediate stimulus–transcription …