Context: Various drugs affect body weight as a side effect. Objective: We conducted this
systematic review and meta-analysis to summarize the evidence about commonly …

Objective: To assess the evidence demonstrating efficacy, tolerability, and safety of seven
new antiepileptic drugs (AEDs)(gabapentin, lamotrigine, topiramate, tiagabine …

Recent advances in molecular biology and complementary information derived from
neuropharmacology, biochemistry and behavior have dramatically increased our …

With the introduction of several new antiepileptic drugs into clinical practice, renewed
attention has been focussed on treatment-emergent adverse effects, including mood …

Objective: To evaluate the efficacy and safety of topiramate as adjunctive therapy for Lennox–
Gastaut syndrome in a multicenter, double-blind, placebo-controlled trial. Background …

The anticonvulsant topiramate is effective in laboratory animals against maximal
electroshock seizures, amygdala kindling, and spike-wave discharges and has …

ContextThe past decade has brought many advances to the treatment of epilepsy, including
many new pharmacological agents. Primary care physicians often care for patients with …

Objective: To study the acute and steady-state cognitive effects of three new antiepileptic
drugs (AEDs): gabapentin, lamotrigine, and topiramate. Background: Several newer …

Objectives–To compare topiramate (TPM) with investigator's choice of carbamazepine (CBZ)
or valproate (VPA) for initial treatment in patients with newly diagnosed epilepsy. Material …

Background and Objective: Topiramate is effective as adjunctive treatment of partial-onset
seizures in adults. The efficacy and safety of topiramate as adjunctive therapy for the …