Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

[HTML][HTML] Advanced application of stimuli-responsive drug delivery system for inflammatory arthritis treatment

M Zhang, W Hu, C Cai, Y Wu, J Li, S Dong - Materials Today Bio, 2022 - Elsevier
Inflammatory arthritis is a major cause of disability in the elderly. This condition causes joint
pain, loss of function, and deterioration of quality of life, mainly due to osteoarthritis (OA) and …

[HTML][HTML] Smart/stimuli-responsive hydrogels: Cutting-edge platforms for tissue engineering and other biomedical applications

HM El-Husseiny, EA Mady, L Hamabe, A Abugomaa… - Materials Today Bio, 2022 - Elsevier
Recently, biomedicine and tissue regeneration have emerged as great advances that
impacted the spectrum of healthcare. This left the door open for further improvement of their …

Recent advances in biopolymer-based hydrogels and their potential biomedical applications

DK Patel, E Jung, S Priya, SY Won, SS Han - Carbohydrate polymers, 2024 - Elsevier
Hydrogels are three-dimensional networks of polymer chains containing large amounts of
water in their structure. Hydrogels have received significant attention in biomedical …

Stimuli‐responsive nanocomposite hydrogels for biomedical applications

P Lavrador, MR Esteves, VM Gaspar… - Advanced Functional …, 2021 - Wiley Online Library
The complex tissue‐specific physiology that is orchestrated from the nano‐to the
macroscale, in conjugation with the dynamic biophysical/biochemical stimuli underlying …

Neutrophil hitchhiking for drug delivery to the bone marrow

Z Luo, Y Lu, Y Shi, M Jiang, X Shan, X Li… - Nature …, 2023 - nature.com
Pharmaceuticals have been developed for the treatment of a wide range of bone diseases
and disorders, but suffer from problematic delivery to the bone marrow. Neutrophils are …

Near-infrared photoactivated nanomedicines for photothermal synergistic cancer therapy

H Sun, Q Zhang, J Li, S Peng, X Wang, R Cai - Nano Today, 2021 - Elsevier
Cancer nanomedicines have provided promising treatment strategies for the regression of
several types of cancer, although there still exists a need for significant advances to improve …

Rational design of bisphosphonate lipid-like materials for mRNA delivery to the bone microenvironment

L Xue, N Gong, SJ Shepherd, X **ong… - Journal of the …, 2022 - ACS Publications
The development of lipid nanoparticle (LNP) formulations for targeting the bone
microenvironment holds significant potential for nucleic acid therapeutic applications …

Nanoarchitecture-integrated hydrogel systems toward therapeutic applications

H Zhu, J Zheng, XY Oh, CY Chan, BQL Low, JQ Tor… - ACS …, 2023 - ACS Publications
Hydrogels, as one of the most feasible soft biomaterials, have gained considerable attention
in therapeutic applications by virtue of their tunable properties including superior patient …

Bone physiology as inspiration for tissue regenerative therapies

D Lopes, C Martins-Cruz, MB Oliveira, JF Mano - Biomaterials, 2018 - Elsevier
The development, maintenance of healthy bone and regeneration of injured tissue in the
human body comprise a set of intricate and finely coordinated processes. However, an …