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Short-chain fatty acids: linking diet, the microbiome and immunity
The short-chain fatty acids (SCFAs) butyrate, propionate and acetate are microbial
metabolites and their availability in the gut and other organs is determined by environmental …
metabolites and their availability in the gut and other organs is determined by environmental …
Microbiota in health and diseases
The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …
since its discovery. Depending on the localized regions, microbiota can be classified into …
Gut microbiota and short chain fatty acids: implications in glucose homeostasis
Gut microbiota encompasses a wide variety of commensal microorganisms consisting of
trillions of bacteria, fungi, and viruses. This microbial population coexists in symbiosis with …
trillions of bacteria, fungi, and viruses. This microbial population coexists in symbiosis with …
[HTML][HTML] Butyrate's role in human health and the current progress towards its clinical application to treat gastrointestinal disease
K Hodgkinson, F El Abbar, P Dobranowski… - Clinical Nutrition, 2023 - Elsevier
Butyrate is a key energy source for colonocytes and is produced by the gut microbiota
through fermentation of dietary fiber. Butyrate is a histone deacetylase inhibitor and also …
through fermentation of dietary fiber. Butyrate is a histone deacetylase inhibitor and also …
A review of gut microbiota‐derived metabolites in tumor progression and cancer therapy
Q Yang, B Wang, Q Zheng, H Li, X Meng… - Advanced …, 2023 - Wiley Online Library
Gut microbiota‐derived metabolites are key hubs connecting the gut microbiome and cancer
progression, primarily by remodeling the tumor microenvironment and regulating key …
progression, primarily by remodeling the tumor microenvironment and regulating key …
Lipid metabolism in T cell signaling and function
T cells orchestrate adaptive immunity against pathogens and other immune challenges, but
their dysfunction can also mediate the pathogenesis of cancer and autoimmunity. Metabolic …
their dysfunction can also mediate the pathogenesis of cancer and autoimmunity. Metabolic …
A mechanism by which gut microbiota elevates permeability and inflammation in obese/diabetic mice and human gut
Objective Ample evidence exists for the role of abnormal gut microbiota composition and
increased gut permeability ('leaky gut') in chronic inflammation that commonly co-occurs in …
increased gut permeability ('leaky gut') in chronic inflammation that commonly co-occurs in …
Clostridioides difficile infection: history, epidemiology, risk factors, prevention, clinical manifestations, treatment, and future options
S Di Bella, G Sanson, J Monticelli… - Clinical Microbiology …, 2024 - journals.asm.org
Clostridioides difficile infection (CDI) is one of the major issues in nosocomial infections.
This bacterium is constantly evolving and poses complex challenges for clinicians, often …
This bacterium is constantly evolving and poses complex challenges for clinicians, often …
Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites
INTRODUCTION The toxicity of high-dose ionizing radiation is associated with the induction
of both chronic and acute radiation syndromes that occur after partial or total body radiation …
of both chronic and acute radiation syndromes that occur after partial or total body radiation …
Lachnospiraceae-derived butyrate mediates protection of high fermentable fiber against placental inflammation in gestational diabetes mellitus
S Huang, J Chen, Z Cui, K Ma, D Wu, J Luo, F Li… - Science …, 2023 - science.org
Inflammation-associated insulin resistance is a key trigger of gestational diabetes mellitus
(GDM), but the underlying mechanisms and effective interventions remain unclear. Here, we …
(GDM), but the underlying mechanisms and effective interventions remain unclear. Here, we …