Heart failure is a global problem with an estimated prevalence of 38 million patients
worldwide, a number that is increasing with the ageing of the population. It is the most …

Multipotent mesenchymal stromal/stem cells (MSCs) reside in many human organs and
comprise heterogeneous population of cells with self‐renewal ability. These cells can be …

Background At least four laboratories have shown that endogenous cardiac progenitor cells
(CPCs) can be grown directly from adult heart tissue in primary culture, as cardiospheres or …

Stem cells have the potential to differentiate into cardiovascular cell lineages and to
stimulate tissue regeneration in a paracrine/autocrine manner; thus, they have been …

Background—Human cardiac progenitor cells (hCPCs) may promote myocardial
regeneration in adult ischemic myocardium. The regenerative capacity of hCPCs in young …

Stem cells are defined as precursor cells that have the capacity to self-renew and to
generate multiple mature cell types. Only after collecting and culturing tissues is it possible …

Background It has long been thought that mammalian cardiomyocytes are terminally-
differentiated and unable to proliferate. However, myocytes in more primitive animals such …

Stem cell therapy has recently emerged as an innovative strategy over conventional
cardiovascular treatments to restore cardiac function in patients affected by ischemic heart …

The adult heart contains reservoirs of progenitor cells that express embryonic and stem cell-
related antigens. While these antigenically-purified cells are promising candidates for …

Objectives: The goal of this study is to characterize resident cardiac stem cells (CSCs) and
investigate their therapeutic efficacy in myocardial infarction by molecular imaging methods …