Remodelling of the immune system with age—immunosenescence—is a substantial
contributor to poor health in older adults, with increasing risk of infections, cancer and …

Obesity predisposes for atrial fibrillation, heart failure, sudden cardiac death, renal disease
and ischemic stroke, which are the main causes of cardiovascular hospitalization and …

'How Emotions Are Made did what all great books do. It took a subject I thought I understood
and turned my understanding upside down'–Malcolm Gladwell, author of The Tip** Point …

Non-communicable diseases (NCDs)(mainly cardiovascular diseases, cancers, chronic
respiratory diseases and type 2 diabetes) are the main causes of death worldwide. Their …

Exercise training is one of the few therapeutic interventions that improves health span by
delaying the onset of age-related diseases and preventing early death. The length of …

Systematic physical activity increases physical fitness and exercise capacity that lead to the
improvement of health status and athletic performance. Considerable effort is devoted to …

Despite the achieved progress in develo** efficient MDM2-p53 protein-protein interaction
inhibitors (MDM2 inhibitors), the acquired resistance of tumor cells to such p53 activators …

Telomeres protect genomic stability and shortening is one of the hallmarks of ageing.
Telomerase reverse transcriptase (TERT) is the major protein component of telomerase …

As the world demographic structure is getting older, highlighting strategies to counteract age-
related diseases is a major public health concern. Telomeres are nucleoprotein structures …

Well-developed theories are necessary to guide the public in increasing physical activity
(PA) and promoting physical health. The role of positive affective variables (PAVs) in …