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Secondary osteoporosis
Osteoporosis is a global public health problem, with fractures contributing to significant
morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …
morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …
Molecular mechanosensors in osteocytes
L Qin, W Liu, H Cao, G ** endochondral and intramembranous bones
GL Galea, MR Zein, S Allen… - Developmental …, 2021 - Wiley Online Library
Skeletal elements have a diverse range of shapes and sizes specialized to their various
roles including protecting internal organs, locomotion, feeding, hearing, and vocalization …
roles including protecting internal organs, locomotion, feeding, hearing, and vocalization …
Exercise early and often: effects of physical activity and exercise on women's bone health
KL Troy, ME Mancuso, TA Butler… - International journal of …, 2018 - mdpi.com
In 2011 over 1.7 million people were hospitalized because of a fragility fracture, and direct
costs associated with osteoporosis treatment exceeded 70 billion dollars in the United …
costs associated with osteoporosis treatment exceeded 70 billion dollars in the United …
[BOK][B] Skeletal tissue mechanics
RB Martin, DB Burr, NA Sharkey, DP Fyhrie - 1998 - Springer
The first edition of Skeletal Tissue Mechanics, published in 1998, grew out of Bruce Martin's
lecture notes for a course by the same name, which was part of the biomedical engineering …
lecture notes for a course by the same name, which was part of the biomedical engineering …
Mechanical regulation of signaling pathways in bone
A wide range of cell types depend on mechanically induced signals to enable appropriate
physiological responses. The skeleton is particularly dependent on mechanical information …
physiological responses. The skeleton is particularly dependent on mechanical information …
Osteocytes and estrogen deficiency
LM McNamara - Current osteoporosis reports, 2021 - Springer
Abstract Purpose of Review Postmenopausal osteoporosis reduces circulating estrogen
levels, which leads to osteoclast resorption, bone loss, and fracture. This review addresses …
levels, which leads to osteoclast resorption, bone loss, and fracture. This review addresses …
[HTML][HTML] Regulation of skeletal development and maintenance by Runx2 and Sp7
T Komori - International Journal of Molecular Sciences, 2024 - mdpi.com
Runx2 (runt related transcription factor 2) and Sp7 (Sp7 transcription factor 7) are crucial
transcription factors for bone development. The cotranscription factor Cbfb (core binding …
transcription factors for bone development. The cotranscription factor Cbfb (core binding …
Mechanically induced Ca2+ oscillations in osteocytes release extracellular vesicles and enhance bone formation
AE Morrell, GN Brown, ST Robinson, RL Sattler… - Bone research, 2018 - nature.com
The vast osteocytic network is believed to orchestrate bone metabolic activity in response to
mechanical stimuli through production of sclerostin, RANKL, and osteoprotegerin (OPG) …
mechanical stimuli through production of sclerostin, RANKL, and osteoprotegerin (OPG) …