Association of obesity with survival outcomes in patients with cancer: a systematic review and meta-analysis
Importance Obesity, defined as a body mass index (BMI) greater than 30, is associated with
a significant increase in the risk of many cancers and in overall mortality. However, various …
a significant increase in the risk of many cancers and in overall mortality. However, various …
The clinical value of nutritional care before and during active cancer treatment
Malnutrition and muscle wasting are frequently reported in cancer patients, either linked to
the tumor itself or caused by oncologic therapies. Understanding the value of nutritional care …
the tumor itself or caused by oncologic therapies. Understanding the value of nutritional care …
The effect of concomitant use of statins, NSAIDs, low-dose aspirin, metformin and beta-blockers on outcomes in patients receiving immune checkpoint inhibitors: a …
Y Zhang, H Chen, S Chen, Z Li, J Chen, W Li - Oncoimmunology, 2021 - Taylor & Francis
Immunotherapy shows promising therapeutic efficacy against various types of cancer, but
most fail to respond. Preclinical studies have suggested that concomitant medications, such …
most fail to respond. Preclinical studies have suggested that concomitant medications, such …
Insulin and cancer: a tangled web
For a century, since the pioneering work of Otto Warburg, the interwoven relationship
between metabolism and cancer has been appreciated. More recently, with obesity rates …
between metabolism and cancer has been appreciated. More recently, with obesity rates …
The impact of race, ethnicity, and obesity on CAR T-cell therapy outcomes
Cancer outcomes with chemotherapy are inferior in patients of minority racial/ethnic groups
and those with obesity. Chimeric antigen receptor (CAR) T-cell therapy has transformed …
and those with obesity. Chimeric antigen receptor (CAR) T-cell therapy has transformed …
[HTML][HTML] Immunoregulation in cancer-associated cachexia
Background Cancer-associated cachexia is a multi-organ disorder associated with
progressive weight loss due to a variable combination of anorexia, systemic inflammation …
progressive weight loss due to a variable combination of anorexia, systemic inflammation …
Influence of adipose tissue distribution, sarcopenia, and nutritional status on clinical outcomes after CD19 CAR T-cell therapy
K Rejeski, DM Cordas dos Santos, NH Parker… - Cancer Immunology …, 2023 - AACR
Although CD19-directed chimeric antigen receptor T-cell therapy (CD19. CAR-T) has proven
clinical efficacy for multiple refractory B-cell malignancies, over 50% of patients ultimately …
clinical efficacy for multiple refractory B-cell malignancies, over 50% of patients ultimately …
Nutritional status as a predictive biomarker for immunotherapy outcomes in advanced head and neck cancer
M Guller, M Herberg, N Amin, H Alkhatib, C Maroun… - Cancers, 2021 - mdpi.com
Simple Summary Tumors of head and neck cancer are a heterogenous collection of
malignancies affecting the upper aerodigestive tract, the majority of which are head and …
malignancies affecting the upper aerodigestive tract, the majority of which are head and …
Smoking status during first‐line immunotherapy and chemotherapy in NSCLC patients: A case–control matched analysis from a large multicenter study
Background Improved outcome in tobacco smoking patients with non‐small cell lung cancer
(NSCLC) following immunotherapy has previously been reported. However, little is known …
(NSCLC) following immunotherapy has previously been reported. However, little is known …
Obesity is associated with altered tumor metabolism in metastatic melanoma
AW Hahn, AV Menk, DB Rivadeneira, RC Augustin… - Clinical Cancer …, 2023 - AACR
Abstract Purpose: Overweight/obese (OW/OB) patients with metastatic melanoma
unexpectedly have improved outcomes with immune checkpoint inhibitors (ICI) and BRAF …
unexpectedly have improved outcomes with immune checkpoint inhibitors (ICI) and BRAF …