Association of obesity with survival outcomes in patients with cancer: a systematic review and meta-analysis

F Petrelli, A Cortellini, A Indini, G Tomasello… - JAMA network …, 2021 - jamanetwork.com
Importance Obesity, defined as a body mass index (BMI) greater than 30, is associated with
a significant increase in the risk of many cancers and in overall mortality. However, various …

The clinical value of nutritional care before and during active cancer treatment

G Aprile, D Basile, R Giaretta, G Schiavo, N La Verde… - Nutrients, 2021 - mdpi.com
Malnutrition and muscle wasting are frequently reported in cancer patients, either linked to
the tumor itself or caused by oncologic therapies. Understanding the value of nutritional care …

The effect of concomitant use of statins, NSAIDs, low-dose aspirin, metformin and beta-blockers on outcomes in patients receiving immune checkpoint inhibitors: a …

Y Zhang, H Chen, S Chen, Z Li, J Chen, W Li - Oncoimmunology, 2021 - Taylor & Francis
Immunotherapy shows promising therapeutic efficacy against various types of cancer, but
most fail to respond. Preclinical studies have suggested that concomitant medications, such …

Insulin and cancer: a tangled web

BP Leitner, S Siebel, ND Akingbesote… - Biochemical …, 2022 - portlandpress.com
For a century, since the pioneering work of Otto Warburg, the interwoven relationship
between metabolism and cancer has been appreciated. More recently, with obesity rates …

The impact of race, ethnicity, and obesity on CAR T-cell therapy outcomes

AJ Faruqi, JA Ligon, P Borgman, SM Steinberg… - Blood …, 2022 - ashpublications.org
Cancer outcomes with chemotherapy are inferior in patients of minority racial/ethnic groups
and those with obesity. Chimeric antigen receptor (CAR) T-cell therapy has transformed …

[HTML][HTML] Immunoregulation in cancer-associated cachexia

Q Wu, Z Liu, B Li, Y Liu, P Wang - Journal of Advanced Research, 2024 - Elsevier
Background Cancer-associated cachexia is a multi-organ disorder associated with
progressive weight loss due to a variable combination of anorexia, systemic inflammation …

Influence of adipose tissue distribution, sarcopenia, and nutritional status on clinical outcomes after CD19 CAR T-cell therapy

K Rejeski, DM Cordas dos Santos, NH Parker… - Cancer Immunology …, 2023 - AACR
Although CD19-directed chimeric antigen receptor T-cell therapy (CD19. CAR-T) has proven
clinical efficacy for multiple refractory B-cell malignancies, over 50% of patients ultimately …

Nutritional status as a predictive biomarker for immunotherapy outcomes in advanced head and neck cancer

M Guller, M Herberg, N Amin, H Alkhatib, C Maroun… - Cancers, 2021 - mdpi.com
Simple Summary Tumors of head and neck cancer are a heterogenous collection of
malignancies affecting the upper aerodigestive tract, the majority of which are head and …

Smoking status during first‐line immunotherapy and chemotherapy in NSCLC patients: A case–control matched analysis from a large multicenter study

A Cortellini, A De Giglio, K Cannita… - Thoracic …, 2021 - Wiley Online Library
Background Improved outcome in tobacco smoking patients with non‐small cell lung cancer
(NSCLC) following immunotherapy has previously been reported. However, little is known …

Obesity is associated with altered tumor metabolism in metastatic melanoma

AW Hahn, AV Menk, DB Rivadeneira, RC Augustin… - Clinical Cancer …, 2023 - AACR
Abstract Purpose: Overweight/obese (OW/OB) patients with metastatic melanoma
unexpectedly have improved outcomes with immune checkpoint inhibitors (ICI) and BRAF …