Horizontal gene transfer and adaptive evolution in bacteria
Horizontal gene transfer (HGT) is arguably the most conspicuous feature of bacterial
evolution. Evidence for HGT is found in most bacterial genomes. Although HGT can …
evolution. Evidence for HGT is found in most bacterial genomes. Although HGT can …
Horizontal gene transfer and the evolution of bacterial and archaeal population structure
Many bacterial and archaeal lineages have a history of extensive and ongoing horizontal
gene transfer and loss, as evidenced by the large differences in genome content even …
gene transfer and loss, as evidenced by the large differences in genome content even …
Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis
M. tuberculosis is evolving antibiotic resistance, threatening attempts at tuberculosis
epidemic control. Mechanisms of resistance, including genetic changes favored by selection …
epidemic control. Mechanisms of resistance, including genetic changes favored by selection …
Population genomics of early events in the ecological differentiation of bacteria
Genetic exchange is common among bacteria, but its effect on population diversity during
ecological differentiation remains controversial. A fundamental question is whether …
ecological differentiation remains controversial. A fundamental question is whether …
Mobile genes in the human microbiome are structured from global to individual scales
Recent work has underscored the importance of the microbiome in human health, and has
largely attributed differences in phenotype to differences in the species present among …
largely attributed differences in phenotype to differences in the species present among …
Clinical sequencing uncovers origins and evolution of Lassa virus
Summary The 2013–2015 West African epidemic of Ebola virus disease (EVD) reminds us
of how little is known about biosafety level 4 viruses. Like Ebola virus, Lassa virus (LASV) …
of how little is known about biosafety level 4 viruses. Like Ebola virus, Lassa virus (LASV) …
Explaining microbial genomic diversity in light of evolutionary ecology
Comparisons of closely related microorganisms have shown that individual genomes can be
highly diverse in terms of gene content. In this Review, we discuss several studies showing …
highly diverse in terms of gene content. In this Review, we discuss several studies showing …
Bacterial motility can govern the dynamics of antibiotic resistance evolution
Spatial heterogeneity in antibiotic concentrations is thought to accelerate the evolution of
antibiotic resistance, but current theory and experiments have overlooked the effect of cell …
antibiotic resistance, but current theory and experiments have overlooked the effect of cell …
A reverse ecology approach based on a biological definition of microbial populations
Delineating ecologically meaningful populations among microbes is important for identifying
their roles in environmental and host-associated microbiomes. Here, we introduce a metric …
their roles in environmental and host-associated microbiomes. Here, we introduce a metric …
Environmental stress leads to genome streamlining in a widely distributed species of soil bacteria
AK Simonsen - The ISME Journal, 2022 - academic.oup.com
Bacteria have highly flexible pangenomes, which are thought to facilitate evolutionary
responses to environmental change, but the impacts of environmental stress on pangenome …
responses to environmental change, but the impacts of environmental stress on pangenome …