Cap** protein (CP) binds the fast growing barbed end of the actin filament and regulates
actin assembly by blocking the addition and loss of actin subunits. Recent studies provide …
actin assembly by blocking the addition and loss of actin subunits. Recent studies provide …
Structures of the free and capped ends of the actin filament
The barbed and pointed ends of the actin filament (F-actin) are the sites of growth and
shrinkage and the targets of cap** proteins that block subunit exchange, including CapZ …
shrinkage and the targets of cap** proteins that block subunit exchange, including CapZ …
Filopodia in vitro and in vivo
TCA Blake, JL Gallop - Annual Review of Cell and …, 2023 - annualreviews.org
Filopodia are dynamic cell surface protrusions used for cell motility, pathogen infection, and
tissue development. The molecular mechanisms determining how and where filopodia grow …
tissue development. The molecular mechanisms determining how and where filopodia grow …
Actin bundles dynamics and architecture
Cells use the actin cytoskeleton for many of their functions, including their division,
adhesion, mechanosensing, endo-and phagocytosis, migration, and invasion. Actin bundles …
adhesion, mechanosensing, endo-and phagocytosis, migration, and invasion. Actin bundles …
Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion
Cell migration entails networks and bundles of actin filaments termed lamellipodia and
microspikes or filopodia, respectively, as well as focal adhesions, all of which recruit …
microspikes or filopodia, respectively, as well as focal adhesions, all of which recruit …