The evolution of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
The evolution and biology of SARS-CoV-2 variants
Our understanding of the still unfolding severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) pandemic would have been extremely limited without the study of the …
(SARS-CoV-2) pandemic would have been extremely limited without the study of the …
Characterisation of SARS-CoV-2 variants in Bei**g during 2022: an epidemiological and phylogenetic analysis
Y Pan, L Wang, Z Feng, H Xu, F Li, Y Shen, D Zhang… - The lancet, 2023 - thelancet.com
Background Due to the national dynamic zero-COVID strategy in China, there were no
persistent local transmissions of SARS-CoV-2 in Bei**g before December, 2022. However …
persistent local transmissions of SARS-CoV-2 in Bei**g before December, 2022. However …
Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ. 1.1 variant
In late 2022, various Omicron subvariants emerged and cocirculated worldwide. These
variants convergently acquired amino acid substitutions at critical residues in the spike …
variants convergently acquired amino acid substitutions at critical residues in the spike …
Deep-learning-enabled protein–protein interaction analysis for prediction of SARS-CoV-2 infectivity and variant evolution
Host–pathogen interactions and pathogen evolution are underpinned by protein–protein
interactions between viral and host proteins. An understanding of how viral variants affect …
interactions between viral and host proteins. An understanding of how viral variants affect …
Sequential intrahost evolution and onward transmission of SARS-CoV-2 variants
Persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have
been reported in immune-compromised individuals and people undergoing immune …
been reported in immune-compromised individuals and people undergoing immune …
Fitness effects of mutations to SARS-CoV-2 proteins
Abstract Knowledge of the fitness effects of mutations to SARS-CoV-2 can inform
assessment of new variants, design of therapeutics resistant to escape, and understanding …
assessment of new variants, design of therapeutics resistant to escape, and understanding …
Conceptual and empirical bridges between micro-and macroevolution
Explaining broad molecular, phenotypic and species biodiversity patterns necessitates a
unifying framework spanning multiple evolutionary scales. Here we argue that although …
unifying framework spanning multiple evolutionary scales. Here we argue that although …
A delicate balance between antibody evasion and ACE2 affinity for Omicron BA. 2.75
Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have caused
successive global waves of infection. These variants, with multiple mutations in the spike …
successive global waves of infection. These variants, with multiple mutations in the spike …
Generation of SARS-CoV-2 escape mutations by monoclonal antibody therapy
COVID-19 patients at risk of severe disease may be treated with neutralising monoclonal
antibodies (mAbs). To minimise virus escape from neutralisation these are administered as …
antibodies (mAbs). To minimise virus escape from neutralisation these are administered as …