Food allergy: immune mechanisms, diagnosis and immunotherapy

W Yu, DMH Freeland, KC Nadeau - Nature Reviews Immunology, 2016 - nature.com
Food allergy is a pathological, potentially deadly, immune reaction triggered by normally
innocuous food protein antigens. The prevalence of food allergies is rising and the standard …

Immunology of food allergy

L Tordesillas, MC Berin, HA Sampson - Immunity, 2017 - cell.com
Many consider food allergy as the" second wave" of the allergy epidemic following the" first
wave" of respiratory allergy, ie, asthma and allergic rhinitis, plaguing westernized countries …

Sustained outcomes in oral immunotherapy for peanut allergy (POISED study): a large, randomised, double-blind, placebo-controlled, phase 2 study

RS Chinthrajah, N Purington, S Andorf, A Long… - The Lancet, 2019 - thelancet.com
Background Dietary avoidance is recommended for peanut allergies. We evaluated the
sustained effects of peanut allergy oral immunotherapy (OIT) in a randomised long-term …

Food allergy and intolerance: A narrative review on nutritional concerns

D Gargano, R Appanna, A Santonicola… - Nutrients, 2021 - mdpi.com
Adverse food reactions include immune-mediated food allergies and non-immune-mediated
intolerances. However, this distinction and the involvement of different pathogenetic …

Immunological outcomes of allergen-specific immunotherapy in food allergy

AMM Schoos, D Bullens, BL Chawes, J Costa… - Frontiers in …, 2020 - frontiersin.org
IgE-mediated food allergies are caused by adverse immunologic responses to food proteins.
Allergic reactions may present locally in different tissues such as skin, gastrointestinal and …

Food allergy

OI Iweala, SK Choudhary, SP Commins - Current gastroenterology reports, 2018 - Springer
Abstract Purpose of Review The goal of this review is to present an updated summary of the
natural history of major childhood and adult food allergies and report recent advances in …

BSACI 2021 guideline for the management of egg allergy

SC Leech, PW Ewan, IJ Skypala… - Clinical & …, 2021 - Wiley Online Library
This guideline advises on the management of patients with egg allergy. Most commonly egg
allergy presents in infancy, with a prevalence of approximately 2% in children and 0.1% in …

Advances and highlights in allergen immunotherapy: on the way to sustained clinical and immunologic tolerance

M Berings, C Karaaslan, C Altunbulakli… - Journal of Allergy and …, 2017 - Elsevier
Allergen immunotherapy (AIT) is an effective treatment strategy for allergic diseases and has
been used for more than 100 years. In recent years, however, the expectations on concepts …

Targeting type 2 immunity and the future of food allergy treatment

MC Berin - Journal of Experimental Medicine, 2023 - rupress.org
IgE-mediated food allergy affects 6–8% of the population in the United States. Type 2
immune responses are central to the pathogenesis of food allergy, but type 2 CD4+ T cell …

Follow-up to adolescence after early peanut introduction for allergy prevention

G Du Toit, MF Huffaker, S Radulovic, M Feeney… - NEJM …, 2024 - evidence.nejm.org
Background A randomized trial demonstrated consumption of peanut from infancy to age 5
years prevented the development of peanut allergy. An extension of that trial demonstrated …