Bioactive substances such as probiotics are becoming a research hotspot in the field of
tissue regeneration due to their excellent regulatory functions. Here, we proposed to load …

Efficient local delivery of mesenchymal stem cells (MSCs) is a decisive factor for their
application in regeneration processes. Here, we prepared a biomimetic bilayer silk …

Patients' suffering from large or deep wounds caused by traumatic and/or thermal injuries
have significantly lower chances of recapitulating lost skin function through natural healing …

Background Keloid is a pathological skin scar formation with complex and unclear molecular
pathology mechanism. Novel biomarkers and associated mechanisms are needed to …

Corneal ulcers, characterized by severe inflammation of the cornea, can lead to serious,
debilitating complications and may be vision-threatening for horses. In this study, we aimed …

Abstract TNF‐stimulated gene (TSG‐6) was reported to suppress hypertrophic scar (HS)
formation in a rabbit ear model, and the overexpression of TSG‐6 in human HS fibroblasts …

Background A keloid is a type of pathological scar often caused by abnormal tissue repair
after a skin injury and is more common in genetically susceptible individuals. cAMP is a …

INTRODUCTION The medico-economic burden related to wound healing is enormous and
rapidly growing. As the average population ages—with a concomitant increase in …

Epicertin (EPT) is a recombinant variant of the cholera toxin B subunit with a C-terminal
KDEL endoplasmic retention motif. Previously, orally administered EPT demonstrated …