A common hallmark of age‐dependent neurodegenerative diseases is an impairment of
adult neurogenesis. Wingless‐type mouse mammary tumor virus integration site (Wnt)/β …

The evolutionarily conserved Wnt signaling pathway plays a central role in development and
adult tissue homeostasis across species. Wnt proteins are secreted, lipid-modified signaling …

Mesenchymal stem cell-derived exosomes (MSC-Ex) play important roles in tissue injury
repair, however, the roles of MSC-Ex in skin damage repair and its mechanisms are largely …

The Dishevelled protein regulates many developmental processes in animals ranging from
Hydra to humans. Here, we discuss the various known signaling activities of this enigmatic …

Cell to cell communication is vital throughout the development of multicellular organisms
and during adult homeostasis. One way in which communication is achieved is through the …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a progressive
deterioration of cognitive abilities, accumulation of the amyloid-β-peptide (Aβ) and synaptic …

Wnt signaling determines major developmental processes in the embryonic state and
regulates maintenance, self-renewal and differentiation of adult mammalian tissue stem …

The wingless/int1 (WNT)/F rizzled (FZD) signalling pathway controls numerous cellular
processes such as proliferation, differentiation, cell‐fate decisions, migration and plays a …

The Frizzled (FZD) family of receptors is critically involved in embryogenesis, and there is
substantial evidence that members of this family also regulate tissue homeostasis in many …

WNT-5A plays critical roles in a myriad of processes from embryonic morphogenesis to the
maintenance of post-natal homeostasis. WNT-5A knock-out mice fail to survive and present …