Metabolic syndrome and cognitive decline in the elderly: a systematic review

N Assuncao, FK Sudo, C Drummond, FG de Felice… - PloS one, 2018 - journals.plos.org
Background Metabolic Syndrome (MetS) refers to a cluster of metabolic disturbances which
is associated with increased risk for vascular and degenerative conditions in general …

Aging, synaptic dysfunction, and insulin-like growth factor (IGF)-1

F Deak, WE Sonntag - Journals of Gerontology Series A …, 2012 - academic.oup.com
Insulin-like growth factor (IGF)-1 is an important neurotrophic hormone. Deficiency of this
hormone has been reported to influence the genesis of cognitive impairment and dementia …

Dietary fat types and 4‐year cognitive change in community‐dwelling older women

OI Okereke, BA Rosner, DH Kim, JH Kang… - Annals of …, 2012 - Wiley Online Library
Objective: A study was undertaken to relate dietary fat types to cognitive change in healthy
community‐based elders. Methods: Among 6,183 older participants in the Women's Health …

Metabolic syndrome, mild cognitive impairment and Alzheimer's disease—The emerging role of systemic low-grade inflammation and adiposity

B Misiak, J Leszek, A Kiejna - Brain research bulletin, 2012 - Elsevier
The past decade has shed new light on the etiology of Alzheimer's disease (AD), which is
the consequence of interactions between numerous lesions. There is a growing body of …

Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells

Z Ungvari, Z Tucsek, D Sosnowska… - … Series A: Biomedical …, 2013 - academic.oup.com
Age-related impairment of angiogenesis is likely to play a central role in
cerebromicrovascular rarefaction and development of vascular cognitive impairment, but the …

Metabolic syndrome and longitudinal changes in cognitive function: a systematic review and meta-analysis

M Siervo, SL Harrison, C Jagger… - Journal of …, 2014 - content.iospress.com
Background: Metabolic syndrome (MetS) is associated with an increased risk of coronary
heart diseases and stroke. Results on the association of MetS with dementia and cognitive …

The emerging role of dietary fructose in obesity and cognitive decline

SE Lakhan, A Kirchgessner - Nutrition journal, 2013 - Springer
The incidence of obesity has increased dramatically over the past several years, and in
parallel, so has the prevalence of type 2 diabetes (T2D). Numerous studies have …

Cardiovascular disease risk models and longitudinal changes in cognition: a systematic review

SL Harrison, J Ding, EYH Tang, M Siervo, L Robinson… - PloS one, 2014 - journals.plos.org
Background Cardiovascular disease and its risk factors have consistently been associated
with poor cognitive function and incident dementia. Whether cardiovascular disease …

Predictor of cognitive impairment: metabolic syndrome or circadian syndrome

Y Liu, B Zang, J Shao, N Ning, L He, Y Ma - BMC geriatrics, 2023 - Springer
Background It was reported that metabolic syndrome increases the risk for cognitive
impairment and circadian rhythm may influence cognition behavior. Identifying the potential …

Triglycerides paradox among the oldest old:“the lower the better?”

YB Lv, C Mao, X Gao, ZX Yin, VB Kraus… - Journal of the …, 2019 - Wiley Online Library
OBJECTIVES Currently, most treatment guidelines suggest lowering hypertriglyceridemia of
any severity, even in elderly individuals. However associations of serum triglycerides (TGs) …