IL‐6: regulator of Treg/Th17 balance

A Kimura, T Kishimoto - European journal of immunology, 2010 - Wiley Online Library
IL‐6 is a pleiotropic cytokine involved in the physiology of virtually every organ system.
Recent studies have demonstrated that IL‐6 has a very important role in regulating the …

Herbal medicine: biomolecular and clinical aspects

IFF Benzie, S Wachtel-Galor - 2011 - books.google.com
Responding to the increased popularity of herbal medicines and other forms of
complementary or alternative medicine world-wide, this reference reviews and evaluates …

Increased expression of interleukin 17 in inflammatory bowel disease

S Fu**o, A Andoh, S Bamba, A Ogawa, K Hata, Y Araki… - Gut, 2003 - gut.bmj.com
Background and aim: Interleukin (IL) 17 is a cytokine which exerts strong proinflammatory
activities. In this study we evaluated changes in IL-17 expression in the inflamed mucosa …

Regulation of adaptive immunity; the role of interleukin-10

THS Ng, GJ Britton, EV Hill, J Verhagen… - Frontiers in …, 2013 - frontiersin.org
Since the discovery of interleukin-10 (IL-10) in the 1980s, a large body of work has led to its
recognition as a pleiotropic immunomodulatory cytokine that affects both the innate and …

[HTML][HTML] The IL-23/Th17 axis in the immunopathogenesis of psoriasis

A Di Cesare, P Di Meglio, FO Nestle - Journal of Investigative Dermatology, 2009 - Elsevier
Abnormal production of inflammatory mediators is believed to play an important role in the
pathogenesis of psoriasis. Emerging data, both in mice and in humans, put the spotlight on a …

Phenotypic and functional features of human Th17 cells

F Annunziato, L Cosmi, V Santarlasci, L Maggi… - The Journal of …, 2007 - rupress.org
T helper (Th) 17 cells represent a novel subset of CD4+ T cells that are protective against
extracellular microbes, but are responsible for autoimmune disorders in mice. However, their …

Th17 cells in human disease

LA Tesmer, SK Lundy, S Sarkar… - Immunological reviews, 2008 - Wiley Online Library
Our understanding of the role of T cells in human disease is undergoing revision as a result
of the discovery of T‐helper 17 (Th17) cells, a unique CD4+ T‐cell subset characterized by …

Curcumin: A natural modulator of immune cells in systemic lupus erythematosus

AA Momtazi-Borojeni, SM Haftcheshmeh… - Autoimmunity …, 2018 - Elsevier
Curcumin is a polyphenol natural product isolated from turmeric, interacting with different
cellular and molecular targets and, consequently, showing a wide range of pharmacological …

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

Y Komiyama, S Nakae, T Matsuki, A Nambu… - The Journal of …, 2006 - journals.aai.org
IL-17 is a proinflammatory cytokine that activates T cells and other immune cells to produce
a variety of cytokines, chemokines, and cell adhesion molecules. This cytokine is …

TH-17 cells in the circle of immunity and autoimmunity

E Bettelli, M Oukka, VK Kuchroo - Nature immunology, 2007 - nature.com
CD4+ effector T cells have been categorized into two subsets: T helper type 1 (TH1) and
TH2. Another subset of T cells that produce interleukin 17 (IL-17;'TH-17 cells') has been …