Analyzing the microbiome of diverse species and environments using next-generation
sequencing techniques has significantly enhanced our understanding on metabolic …

Sequencing-based analyses of microbiomes have traditionally focused on addressing the
question of community membership and profiling taxonomic abundance through amplicon …

Bacteria were first detected in human tumors more than 100 years ago, but the
characterization of the tumor microbiome has remained challenging because of its low …

Delineation of microbial habitats within the soil matrix and characterization of their
environments and metabolic processes are crucial to understand soil functioning, yet their …

The association of gut microbial features with type 2 diabetes (T2D) has been inconsistent
due in part to the complexity of this disease and variation in study design. Even in cases in …

One major limitation of microbial community marker gene sequencing is that it does not
provide direct information on the functional composition of sampled communities. Here, we …

Functional profiles of microbial communities are typically generated using comprehensive
metagenomic or metatranscriptomic sequence read searches, which are time-consuming …

To address how the microbiome might modify the interaction between diet and
cardiometabolic health, we analyzed longitudinal microbiome data from 307 male …

Metagenomics and marker gene approaches, coupled with high-throughput sequencing
technologies, have revolutionized the field of microbial ecology. Metagenomics is a culture …

Background Acetate is a short-chain fatty acid (SCFA) produced by gut bacteria, which has
been implicated in cardio-metabolic health. Here we examine the relationships of circulating …