Nanotechnology enabled radioprotectants to reduce space radiation‐induced reactive oxidative species

B Babu, S Pawar, A Mittal, E Kolanthai… - Wiley …, 2023 - Wiley Online Library
Interest in space exploration has seen substantial growth following recent launch and
operation of modern space technologies. In particular, the possibility of travel beyond low …

Monitoring inflammatory, immune system mediators, and mitochondrial changes related to brain metabolism during space flight

D Tocci, T Ducai, CAB Stoute, G Hopkins… - Frontiers in …, 2024 - frontiersin.org
The possibility of impaired cognitive function during deep space flight missions or while
living on a Martian colony is a critical point of concern and pleads for further research. In …

Mitochondrial dysfunction in Spaceflight Associated Neuro-Ocular Syndrome (SANS): a molecular hypothesis in pathogenesis

E Waisberg, J Ong, M Masalkhi, XW Mao, A Beheshti… - Eye, 2024 - nature.com
Spaceflight-associated neuro-ocular syndrome (SANS) is a condition affecting astronauts
during long-duration spaceflight (LDSF). SANS is characterized by hyperopic refractive shifts …

Toward robust autotuning of noisy quantum dot devices

J Ziegler, T McJunkin, ES Joseph, SS Kalantre… - Physical Review …, 2022 - APS
The current autotuning approaches for quantum dot (QD) devices, while showing some
success, lack an assessment of data reliability. This leads to unexpected failures when noisy …

Simulated microgravity reduces quality of ovarian follicles and oocytes by disrupting communications of follicle cells

K Cheng, X Feng, C Yang, C Ma, S Niu, L Jia, X Yang… - npj …, 2023 - nature.com
Ovarian follicles are the fundamental structures that support oocyte development, and
communications between oocytes and follicle somatic cells are crucial for oogenesis …

Effects of simulated microgravity in vitro on human metaphase II oocytes: an electron microscopy-based study

S Miglietta, L Cristiano, MSB Espinola, MG Masiello… - Cells, 2023 - mdpi.com
Highlights What are the main findings? For the first time, the in vitro effects of simulated
microgravity using a Random Positioning Machine on the ultrastructural features of human …

Retinal blood vessel diameter changes with 60-day head-down bedrest are unaffected by antioxidant nutritional cocktail

T Louwies, P De Boever, R Hasso, MF Tremblay… - npj …, 2024 - nature.com
Long-term human spaceflight can lead to cardiovascular deconditioning, but little is known
about how weightlessness affects microcirculation. In this study, we examined how the …

A review of reinforcement learning in chemistry

S Gow, M Niranjan, S Kanza, JG Frey - Digital Discovery, 2022 - pubs.rsc.org
The growth of machine learning as a tool for research in computational chemistry is well
documented. For many years, this growth was heavily driven by the paradigms of supervised …

Simulated Microgravity Exposure Induces Antioxidant Barrier Deregulation and Mitochondria Enlargement in TCam-2 Cell Spheroids

M Berardini, L Gesualdi, C Morabito, F Ferranti… - Cells, 2023 - mdpi.com
One of the hallmarks of microgravity-induced effects in several cellular models is
represented by the alteration of oxidative balance with the consequent accumulation of …

Detrimental effects of simulated microgravity on mast cell homeostasis and function

M Kim, G Jang, KS Kim, J Shin - Frontiers in immunology, 2022 - frontiersin.org
Exposure to microgravity causes significant alterations in astronauts' immune systems
during spaceflight; however, it is unknown whether microgravity affects mast cell …