Nanoparticles in drug delivery: From history to therapeutic applications

O Afzal, ASA Altamimi, MS Nadeem, SI Alzarea… - Nanomaterials, 2022 - mdpi.com
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …

Layered double hydroxide-based nanomaterials for biomedical applications

T Hu, Z Gu, GR Williams, M Strimaite, J Zha… - Chemical Society …, 2022 - pubs.rsc.org
Against the backdrop of increased public health awareness, inorganic nanomaterials have
been widely explored as promising nanoagents for various kinds of biomedical applications …

Minimally invasive nanomedicine: nanotechnology in photo-/ultrasound-/radiation-/magnetism-mediated therapy and imaging

J Ouyang, A **e, J Zhou, R Liu, L Wang, H Liu… - Chemical Society …, 2022 - pubs.rsc.org
Traditional treatments such as chemotherapy and surgery usually cause severe side effects
and excruciating pain. The emergence of nanomedicines and minimally invasive therapies …

A MgFe‐LDH nanosheet‐incorporated smart thermo‐responsive hydrogel with controllable growth factor releasing capability for bone regeneration

Z Lv, T Hu, Y Bian, G Wang, Z Wu, H Li, X Liu… - Advanced …, 2023 - Wiley Online Library
Although growth factor (GF)‐loaded hydrogels have been explored as promising materials
in repairing bone defects, it still remains challenging to construct smart hydrogels with …

Controlling the biodistribution and clearance of nanomedicines

H Cabral, J Li, K Miyata, K Kataoka - Nature Reviews Bioengineering, 2024 - nature.com
Nanomedicines improve drug bioavailability, the dose–response relationship, targeting
ability, efficacy and safety compared to conventional freely administered drugs …

Mimicking antioxidases and hyaluronan synthase: a zwitterionic nanozyme for photothermal therapy of osteoarthritis

P Yu, Y Li, H Sun, H Zhang, H Kang, P Wang… - Advanced …, 2023 - Wiley Online Library
Restoring joint homeostasis is crucial for relieving osteoarthritis (OA). Current strategies are
limited to unilateral efforts in joint lubrication, inhibition of inflammation, free radicals …

GelMA-based bioactive hydrogel scaffolds with multiple bone defect repair functions: therapeutic strategies and recent advances

B Zhou, X Jiang, X Zhou, W Tan, H Luo, S Lei… - Biomaterials …, 2023 - spj.science.org
Currently, the clinical treatment of critical bone defects attributed to various causes remains
a great challenge, and repairing these defects with synthetic bone substitutes is the most …

Electrical stimulation system based on electroactive biomaterials for bone tissue engineering

X Zhang, T Wang, Z Zhang, H Liu, L Li, A Wang… - Materials Today, 2023 - Elsevier
Traumatic injuries can lead to large bone defects under extreme conditions, which usually
take a long recovery period, while the prognosis is poor. Endogenous electric field, as one …

Microneedle system for tissue engineering and regenerative medicine

Y Zhang, Y Xu, H Kong, J Zhang, HF Chan… - …, 2023 - Wiley Online Library
Global increasing demand for high life quality and length facilitates the development of
tissue engineering and regenerative medicine, which apply multidisciplinary theories and …

Cancer nanomedicine toward clinical translation: Obstacles, opportunities, and future prospects

P Zhang, Y **ao, X Sun, X Lin, S Koo, AV Yaremenko… - Med, 2023 - cell.com
With the integration of nanotechnology into the medical field at large, great strides have
been made in the development of nanomedicines for tackling different diseases, including …