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Computational models in cardiology
The treatment of individual patients in cardiology practice increasingly relies on advanced
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …
Computational modeling of cardiac electrophysiology and arrhythmogenesis: toward clinical translation
The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …
components across multiple spatial (from ion channel to organ) and temporal (from …
Computational techniques for ECG analysis and interpretation in light of their contribution to medical advances
Widely developed for clinical screening, electrocardiogram (ECG) recordings capture the
cardiac electrical activity from the body surface. ECG analysis can therefore be a crucial first …
cardiac electrical activity from the body surface. ECG analysis can therefore be a crucial first …
Modeling cardiac muscle fibers in ventricular and atrial electrophysiology simulations
Since myocardial fibers drive the electric signal propagation throughout the myocardium,
accurately modeling their arrangement is essential for simulating heart electrophysiology …
accurately modeling their arrangement is essential for simulating heart electrophysiology …
Computational models of atrial fibrillation: Achievements, challenges, and perspectives for improving clinical care
Despite significant advances in its detection, understanding and management, atrial
fibrillation (AF) remains a highly prevalent cardiac arrhythmia with a major impact on …
fibrillation (AF) remains a highly prevalent cardiac arrhythmia with a major impact on …
Multiple mechanisms of spiral wave breakup in a model of cardiac electrical activity
It has become widely accepted that the most dangerous cardiac arrhythmias are due to
reentrant waves, ie, electrical wave (s) that recirculate repeatedly throughout the tissue at a …
reentrant waves, ie, electrical wave (s) that recirculate repeatedly throughout the tissue at a …
Ionic determinants of functional reentry in a 2-D model of human atrial cells during simulated chronic atrial fibrillation
SV Pandit, O Berenfeld, JMB Anumonwo, RM Zaritski… - Biophysical journal, 2005 - cell.com
Recent studies suggest that atrial fibrillation (AF) is maintained by fibrillatory conduction
emanating from a small number of high-frequency reentrant sources (rotors). Our goal was …
emanating from a small number of high-frequency reentrant sources (rotors). Our goal was …
Computational techniques for solving the bidomain equations in three dimensions
EJ Vigmond, F Aguel… - IEEE Transactions on …, 2002 - ieeexplore.ieee.org
The bidomain equations are the most complete description of cardiac electrical activity. Their
numerical solution is, however, computationally demanding, especially in three dimensions …
numerical solution is, however, computationally demanding, especially in three dimensions …
Computational modeling of the human atrial anatomy and electrophysiology
This review article gives a comprehensive survey of the progress made in computational
modeling of the human atria during the last 10 years. Modeling the anatomy has emerged …
modeling of the human atria during the last 10 years. Modeling the anatomy has emerged …
From mitochondrial ion channels to arrhythmias in the heart: computational techniques to bridge the spatio-temporal scales
Computer simulations of electrical behaviour in the whole ventricles have become
commonplace during the last few years. The goals of this article are (i) to review the …
commonplace during the last few years. The goals of this article are (i) to review the …