This review aims to address the significant challenges of treating central nervous system
(CNS) disorders such as neurodegenerative diseases, strokes, spinal cord injuries, and …

Parkinson's disease (PD) is one of the most frequent age-associated neurodegenerative
disorder. Presence of α-synuclein-containing aggregates in the substantia nigra pars …

Introduction Parkinson's disease (PD) presents a significant challenge in medical science,
as current treatments are limited to symptom management and often carry significant side …

Acute cognitive impairments termed delirium often occur after inflammatory insults in elderly
patients. While previous preclinical studies suggest mitochondria as a target for reducing …

Stress profoundly impacts various aspects of both physical and psychological well-being.
Our previous study demonstrated that venlafaxine (Vlx) and synbiotic (Syn) treatment …

Peripheral nerve injury with long size defects has been an urgent clinical challenge. With the
development of bioengineering, nanotechnology and additive manufacturing technologies …

Abstract As per the World Health Organization (WHO) estimation, Alzheimer's disease (AD)
will affect 100 million population across the globe by 2050. AD is an incurable …

Lichen simplex chronicus (LSC) presents a challenge in dermatology due to its elusive
pathogenic mechanisms. While associations between circulating inflammatory cytokines …

Neuroinflammation is a complex and multifaceted process that involves dynamic interactions
among various cellular and molecular components. This sophisticated interplay supports …

Parkinson's disease is a progressive neurodegenerative disease that destroys substantia
nigra dopaminergic neurons, causing tremors, bradykinesia, rigidity, and postural instability …