Background This systematic review provides updated insights, from the published literature
in the past 5 years, based on the 2017 European Association of Neuro-Oncology (EANO) …

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Purpose Radiation necrosis (RN) represents a serious post-radiotherapy complication in
patients with brain metastases. Bevacizumab and laser interstitial thermal therapy (LITT) are …

Research regarding the mechanisms of brain damage following radiation treatments for
brain tumors has increased over the years, thus providing a deeper insight into the …

Abstract Purpose The Working Group for Neurooncology of the German Society for
Radiation Oncology (DEGRO; AG NRO) in cooperation with members of the …

Although intravenous bevacizumab (IVBEV) is the most promising treatment for cerebral
radiation necrosis (CRN), there is no conclusion on the optimal dosage. Our retrospective …

Radiation is a commonly used treatment modality for head and neck as well as CNS
tumours, both benign and malignant. As newer oncology treatments such as …

Steroid use is a widely accepted practice for both the treatment and prevention of tumor-
induced edema, but there are many unknowns regarding their current clinical utility with …

Purpose Re-irradiation (reRT) is an effective treatment modality for patients with recurrent
glioma. Data on dose escalation, the use of simulated integrated boost and concomitant …

OBJECTIVE There is an unmet need for safe and rapidly effective therapies for refractory
brain radiation necrosis (RN). The aim of this prospective single-arm phase II trial was to …