Diabetes-Alzheimer's connection in older age: SGLT2 inhibitors as promising modulators of disease pathways
F Mancinetti, D Xenos, M De Fano, A Mazzieri… - Ageing Research …, 2023 - Elsevier
Late-onset Alzheimer's disease (LOAD) is the most frequent cause of dementia in older
persons. Subjects affected by type 2 diabetes mellitus (T2DM) are at higher risk of vascular …
persons. Subjects affected by type 2 diabetes mellitus (T2DM) are at higher risk of vascular …
[HTML][HTML] The Intersection between Frailty, Diabetes, and Hypertension: The Critical Role of Community Geriatricians and Pharmacists in Deprescribing
D Dinarvand, J Panthakey, A Heidari, A Hassan… - Journal of Personalized …, 2024 - mdpi.com
Background: Frailty is a clinical syndrome prevalent among the elderly, characterised by a
decline in physiological reserves and increased susceptibility to stressors, resulting in …
decline in physiological reserves and increased susceptibility to stressors, resulting in …
Glucose transport and utilization in the hippocampus: from neurophysiology to diabetes-related development of dementia
The association of diabetes with cognitive dysfunction has at least 60 years of history, which
started with the observation that children with type 1 diabetes mellitus (T1D), who had …
started with the observation that children with type 1 diabetes mellitus (T1D), who had …
Cognitive disorders in type 1 diabetes: Role of brain glucose variation, insulin activity and glucocorticoid exposure
J Brossaud, P Barat, MP Moisan - Neuroendocrinology, 2024 - karger.com
Background: The number of patients with type 2 diabetes (T2D) and type 1 diabetes (T1D) is
on the rise, partly due to a global increase in new T1D cases among children. Beyond the …
on the rise, partly due to a global increase in new T1D cases among children. Beyond the …
The crosstalk of different mechanisms in cognitive impairment associated with aging, Alzheimer's disease, and related dementias
L Giménez-Llort - Frontiers in aging neuroscience, 2023 - frontiersin.org
In recent years, significant advances have been made in understanding the pathogenesis
and treatment of Alzheimer's disease (AD). Growing evidence indicates that AD is a …
and treatment of Alzheimer's disease (AD). Growing evidence indicates that AD is a …
[HTML][HTML] Alterations in Brain Morphometric Networks and Their Relationship with Memory Dysfunction in Patients with Type 2 Diabetes Mellitus
RY Kim, Y Joo, E Ha, H Hong, C Suh… - Experimental …, 2024 - ncbi.nlm.nih.gov
Cognitive dysfunction, a significant complication of type 2 diabetes mellitus (T2DM), can
potentially manifest even from the early stages of the disease. Despite evidence of global …
potentially manifest even from the early stages of the disease. Despite evidence of global …
Continuous Glucose Monitoring in Comorbid Dementia and Diabetes: The Evidence So Far
B Donat Ergin, K Gadsby-Davis… - Journal of Diabetes …, 2024 - journals.sagepub.com
Background: Type 2 diabetes mellitus (T2DM) and dementia are two of the leading chronic
diseases in aging and are known to influence each other's disease progression. There is …
diseases in aging and are known to influence each other's disease progression. There is …
Effects of prediabetes and type 2 diabetes on cognitive functions
Introduction We aimed to investigate the effect of glycemic impairment in prediabetes on
cognitive impairment and the impact of glycemic control on cognitive function in patients with …
cognitive impairment and the impact of glycemic control on cognitive function in patients with …
[HTML][HTML] Postprandial hypoglycemia as a complication of bariatric and metabolic surgery: a comprehensive review of literature
M Karimi, OK Gargari - Frontiers in Surgery, 2024 - pmc.ncbi.nlm.nih.gov
Postprandial hypoglycemia (PPH) is a challenging and significant complication that can
occur following bariatric and metabolic surgery. Symptoms of PPH are typical of …
occur following bariatric and metabolic surgery. Symptoms of PPH are typical of …
Unlocking hypoglycemia–associated brain microvascular dysfunction: critical insights from proteomic analysis
SSVP Sakamuri, A Sakamuri - Neural Regeneration Research, 2025 - journals.lww.com
Hypoglycemia is characterized by a decline in circulatory glucose levels below standard
physiological thresholds. Mild hypoglycemia, classified as level 1 hypoglycemia, is defined …
physiological thresholds. Mild hypoglycemia, classified as level 1 hypoglycemia, is defined …