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Molecular complexities underlying the vascular complications of diabetes mellitus–A comprehensive review
Diabetes is a chronic disease, characterized by hyperglycemia, which refers to the elevated
levels of glucose in the blood, due to the inability of the body to produce or use insulin …
levels of glucose in the blood, due to the inability of the body to produce or use insulin …
Mangifera indica (Mango): A Promising Medicinal Plant for Breast Cancer Therapy and Understanding Its Potential Mechanisms of Action
Globally, breast cancer is the most common cancer type and is one of the most significant
causes of deaths in women. To date, multiple clinical interventions have been applied …
causes of deaths in women. To date, multiple clinical interventions have been applied …
miRNA signatures associate with pathogenesis and progression of osteosarcoma
KB Jones, Z Salah, S Del Mare, M Galasso… - Cancer …, 2012 - aacrjournals.org
Osteosarcoma remains a leading cause of cancer death in adolescents. Treatment
paradigms and survival rates have not improved in two decades. Driving the lack of …
paradigms and survival rates have not improved in two decades. Driving the lack of …
Influence of miRNA in insulin signaling pathway and insulin resistance: micro‐molecules with a major role in type‐2 diabetes
The prevalence of type‐2 diabetes (T2D) is increasing significantly throughout the globe
since the last decade. This heterogeneous and multifactorial disease, also known as insulin …
since the last decade. This heterogeneous and multifactorial disease, also known as insulin …
[HTML][HTML] Genetic and epigenetic modulations in toxicity: the two-sided roles of heavy metals and polycyclic aromatic hydrocarbons from the environment
This study emphasizes the importance of considering the metabolic and toxicity mechanisms
of environmental concern chemicals in real-life exposure scenarios. Furthermore …
of environmental concern chemicals in real-life exposure scenarios. Furthermore …
Exosomes miR-126a released from MDSC induced by DOX treatment promotes lung metastasis
Z Deng, Y Rong, Y Teng, X Zhuang, A Samykutty, J Mu… - Oncogene, 2017 - nature.com
Acquired resistance to chemotherapy remains a major stumbling block in cancer treatment.
Chronic inflammation has a crucial role in induction of chemoresistance and results, in part …
Chronic inflammation has a crucial role in induction of chemoresistance and results, in part …
Modulation of the osteosarcoma expression phenotype by microRNAs
Background Osteosarcomas are the most common primary malignant tumors of bone and
show multiple and complex genomic aberrations. miRNAs are non-coding RNAs capable of …
show multiple and complex genomic aberrations. miRNAs are non-coding RNAs capable of …
MicroRNA-126-3p/-5p overexpression attenuates blood-brain barrier disruption in a mouse model of middle cerebral artery occlusion
Background and Purpose—Blood-brain barrier (BBB) disruption is a critical pathological
feature after stroke. MicroRNA-126 (miR-126) maintains BBB integrity by regulating …
feature after stroke. MicroRNA-126 (miR-126) maintains BBB integrity by regulating …
MicroRNAs linking inflamm-aging, cellular senescence and cancer
Epidemiological and experimental data demonstrate a strong correlation between age-
related chronic inflammation (inflamm-aging) and cancer development. However, a …
related chronic inflammation (inflamm-aging) and cancer development. However, a …
miR-126 in human cancers: clinical roles and current perspectives
Abstract miR-126 has been implicated in the processes of inflammation and angiogenesis.
Through these processes, miR-126 is implicated in cancer biology, but its role there has not …
Through these processes, miR-126 is implicated in cancer biology, but its role there has not …