Reactive oxygen species (ROS) are highly reactive reduced oxygen molecules that result
from aerobic metabolism. The common forms are the superoxide anion (O2∙−) and hydrogen …

The liver is an important metabolic and detoxification organ and hence demands a large
amount of energy, which is mainly produced by the mitochondria. Liver tissues of patients …

Aims: Ischemia-reperfusion injury (IRI)-induced acute kidney injury (IRI-AKI) is characterized
by elevated levels of reactive oxygen species (ROS), mitochondrial dysfunction, and …

Mitochondrial dysfunction is a key feature of injury to numerous tissues and stem cell aging.
Although the tissue regenerative role of mesenchymal stem cell (MSC)-derived extracellular …

Mitochondrial dysfunction has been widely accepted as a detrimental factor in subarachnoid
hemorrhage (SAH)-induced early brain injury (EBI), which is eminently related to poor …

Enhancing mitochondrial biogenesis and reducing mitochondrial oxidative stress have
emerged as crucial therapeutic strategies to ameliorate diabetic myocardial …

There is growing evidence that mesenchymal stem cell-derived extracellular vesicles and
exosomes can significantly improve the curative effect of oxidative stress-related diseases …

Mitochondrial dysfunction causes the production of reactive oxygen species (ROS) and
oxidative damage, and oxidative stress and inflammation are considered key factors causing …

Rationale: Mitochondrial dysfunction facilitates heart failure development forming a
therapeutic target, but the mechanism involved remains unclear. We studied whether the …

Metabolic syndrome (MetS) is a precursor to the major health diseases associated with high
mortality in industrialized countries: cardiovascular disease and diabetes. An important …