The global pharmaceutical market has recently shifted its focus from small molecule drugs to
peptide, protein, and nucleic acid drugs, which now comprise a majority of the top-selling …

Lysosomes play a central role in cellular homeostasis and alterations in this compartment
associate with many diseases. The most studied example is that of lysosomal storage …

Enzyme‐based therapy has garnered significant attention for its current applications in
various diseases. Despite the notable advantages associated with the use of enzymes as …

Rapid haemorrhage control to restore tissue oxygenation is essential in order to improve
survival following traumatic injury. To this end, the current clinical standard relies on the …

A substantial development in nanoscale materials possessing catalytic activities comparable
with natural enzymes has been accomplished. Their advantages were owing to the excellent …

Herein, our suggestion is to immobilize enzymes in-situ on absorbable shape-memory
stents instead of injecting therapeutic enzymes into the blood. Chitosan (CHI)-based stents …

Microbes are a major source of enzymes due to their ability to be mass-cultivated and
genetically modified. Compared with plant and animal enzymes, microbial enzymes are …

Microbial therapeutic enzymes are the protagonists in the pharmacological treatment of
different human diseases. The intrinsic enzymatic characteristics, such as high affinity and …

Biofilms are complex communities of micro-organisms enclosed in a self-produced matrix of
extra-cellular polymeric substances consisting of polysac-charides, proteins, lipids and …

Microbial therapeutic enzymes are the protagonists in the pharmacological treatment of
different human diseases. The intrinsic enzymatic characteristics, such as high affinity and …