The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Dopamine is well recognized as a neurotransmitter in the brain, and regulates critical
functions in a variety of peripheral systems. Growing research has also shown that …

Advances in the treatment of the human immunodeficiency virus (HIV) have dramatically
improved survival rates over the past 10 years, but HIV-associated neurocognitive disorders …

The current study explored the predictive validity of the Global Deficit Score (GDS) approach
in summarizing neuropsychological (NP) test results, and specifically in detecting HIV …

Neurodegenerative diseases affect millions of people worldwide. Neurodegenerative
diseases result from progressive damage to nerve cells in the brain or peripheral nervous …

Parkinson's disease is a debilitating neurological disorder characterized that affects 1–2% of
the adult population over 55 years of age. For the vast majority of cases, the etiology of this …

The pathogenesis of human immunodeficiency virus (HIV)‐associated dementia is unclear,
and the underlying pathological substrate has been a matter of debate. In a prospectively …

Background: Neurocognitive impairment remains prevalent in HIV-infected (HIV+)
individuals despite highly active antiretroviral therapy (HAART). We assessed the impact of …

Increases in circulating CD14+/CD16+ monocytes have been associated with HIV dementia;
trafficking of these cells into the CNS has been proposed to play an important role in the …

Substance use disorders (SUD) and drug addiction are major threats to public health,
impacting not only the millions of individuals struggling with SUD, but also surrounding …