[HTML][HTML] Poly-l-lactic acid (PLLA)-based biomaterials for regenerative medicine: a review on processing and applications
Synthetic biopolymers are effective cues to replace damaged tissue in the tissue
engineering (TE) field, both for in vitro and in vivo application. Among them, poly-l-lactic acid …
engineering (TE) field, both for in vitro and in vivo application. Among them, poly-l-lactic acid …
[HTML][HTML] Liquid-liquid phase separation: Fundamental physical principles, biological implications, and applications in supramolecular materials engineering
Liquid-liquid phase separation (LLPS) is a captivating phenomenon in which a uniform
mixture spontaneously divides into two liquid phases with differing component …
mixture spontaneously divides into two liquid phases with differing component …
Recent advances in complex coacervation design from macromolecular assemblies and emerging applications
Coacervation is a process during which a homogeneous aqueous solution undergoes liquid–
liquid phase separation, giving rise to two immiscible liquid phases composed of a colloid …
liquid phase separation, giving rise to two immiscible liquid phases composed of a colloid …
Dual delivery of stem cells and insulin-like growth factor-1 in coacervate-embedded composite hydrogels for enhanced cartilage regeneration in osteochondral …
Exogenous dual delivery of progenitor cell population and therapeutic growth factors (GFs)
is one of alternative tissue engineering strategies for osteochondral tissue regeneration. In …
is one of alternative tissue engineering strategies for osteochondral tissue regeneration. In …
Recent advances in synthetic and natural biomaterials‐based therapy for bone defects
MI Alvarez Echazu, O Perna, CE Olivetti… - Macromolecular …, 2022 - Wiley Online Library
Synthetic and natural biomaterials are a promising alternative for the treatment of critical‐
sized bone defects. Several parameters such as their porosity, surface, and mechanical …
sized bone defects. Several parameters such as their porosity, surface, and mechanical …
Coacervate-mediated novel pancreatic cancer drug Aleuria Aurantia lectin delivery for augmented anticancer therapy
Background Pancreatic cancer, one of the cancers with the highest mortality rate, has very
limited clinical treatment. Cancer cells express abnormal glycans on the surface, and some …
limited clinical treatment. Cancer cells express abnormal glycans on the surface, and some …
Hylozoic by design: Converging material and biological complexities for cell‐driven living materials with 4D behaviors
The emergence of novel techniques in biology and material science, coupled with greater
understandings of cell–material interactions, have given rise to the creation of living …
understandings of cell–material interactions, have given rise to the creation of living …
Tumor microenvironment-responsive 6-mercaptopurine-releasing injectable hydrogel for colon cancer treatment
Colon cancer is a significant health concern. The development of effective drug delivery
systems is critical for improving treatment outcomes. In this study, we developed a drug …
systems is critical for improving treatment outcomes. In this study, we developed a drug …
Fabrication parameter-dependent physico-chemical properties of thiolated gelatin/PEGDA interpenetrating network hydrogels
BACKGROUND: The development of three-dimensional hydrogels using polymeric
biomaterials is a key technology for tissue engineering and regenerative medicine …
biomaterials is a key technology for tissue engineering and regenerative medicine …
Enhanced anticancer efficacy of primed natural killer cells via coacervate-mediated exogenous interleukin-15 delivery
Effective exogenous delivery of interleukin (IL)-15 to natural killer (NK) cells with subsequent
anticancer efficacy could be a promising immune cell-based cancer immunotherapy. For the …
anticancer efficacy could be a promising immune cell-based cancer immunotherapy. For the …