[HTML][HTML] Deep eutectic solvents as unconventional media for multicomponent reactions

LS Longo Jr, MV Craveiro - Journal of the Brazilian Chemical Society, 2018 - SciELO Brasil
Regarding all the green aspects of sustainable chemical transformations, eco-friendly
processes along with economic development, environmental protection as well as natural …

1, 3, 4-Thiadiazole: A versatile pharmacophore of medicinal significance

M Bala, P Piplani, A Ankalgi, A Jain… - Medicinal …, 2023 - ingentaconnect.com
The 1, 3, 4-thiadiazole nucleus has attracted the attention of medicinal chemists during the
last decades due to its multiple pharmacological activities, such as antiviral, anticancer …

A comparison between observed and DFT calculations on structure of 5-(4-chlorophenyl)-2-amino-1, 3, 4-thiadiazole

N Kerru, L Gummidi, SVHS Bhaskaruni, SN Maddila… - Scientific Reports, 2019 - nature.com
The crystal and molecular structure of 5-(4-chlorophenyl)-2-amino-1, 3, 4-thiadiazole 3 was
reported, which was characterized by various spectroscopic techniques (FT-IR, NMR and …

Design, synthesis and insecticidal activity of new 1, 3, 4-thiadiazole and 1, 3, 4-thiadiazolo [3, 2-a] pyrimidine derivatives under solvent-free conditions

MF Ismail, HMF Madkour, MS Salem… - Synthetic …, 2021 - Taylor & Francis
(3-Chlorophenyl)-1, 3, 4-thiadiazol-2-amine 2 was synthesized and employed to synthesize
new 1, 3, 4-thiadiazole and 1, 3, 4-thiadiazolo [3, 2-a] pyrimidine derivatives via reactions …

An efficient four component domino synthesis of pyrazolopyranopyrimidines using recyclable choline chloride: Urea deep eutectic solvent

MR Tipale, LD Khillare, AR Deshmukh… - Journal of …, 2018 - Wiley Online Library
An efficient synthesis of pyrazolopyranopyrimidines was achieved by four component
domino reaction of aldehydes, barbituric acid, hydrazine hydrate, and ethyl acetoacetate …

Straightforward synthesis of 2-chloro-N-(5-(cyanomethyl)-1,3,4-thiadiazol-2-yl)benzamide as a precursor for synthesis of novel heterocyclic compounds with …

AMM Mohamed, MF Ismail, HMF Madkour… - Synthetic …, 2020 - Taylor & Francis
The current work is devoted to the synthesis of 2-chloro-N-(5-(cyanomethyl)-1, 3, 4-
thiadiazol-2-yl) benzamide 5 by an efficient synthetic methodology. The authors decided to …

Ketene dithioacetals in organic synthesis

L Huang, J Wu, J Hu, Y Bi, D Huang - Tetrahedron Letters, 2020 - Elsevier
Ketene dithioacetals were widely used in organic reactions. Herein, recent advances were
summarized as five categories according to their triggered mechanisms:(1) nucleophilic …

Urea decomposition: Efficient synthesis of pyrroles using the deep eutectic solvent choline chloride/urea

L Hu, J Luo, D Lu, Q Tang - Tetrahedron Letters, 2018 - Elsevier
Urea decomposition: Efficient synthesis of pyrroles using the deep eutectic solvent choline
chloride/urea - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books …

Bio‐based benzoxazines synthesized in a deep eutectic solvent: A greener approach toward vesicular nanosystems

MS Behalo, E Bloise, G Mele… - Journal of …, 2020 - Wiley Online Library
A green synthesis of benzoxazines, based upon reaction of cardanol with formaldehyde and
primary amines, is achieved in high yields using choline chloride‐urea mixture as deep …

Multicomponent synthetic strategies and perspectives for synthesis of linked or fused coumarin heterocycles

S Pasricha, K Mittal, P Gahlot, H Kaur, N Avasthi… - Journal of the Iranian …, 2022 - Springer
Natural and synthetic hybrid molecules are an attractive scaffold for therapeutic agent
development due to their dual/multiple modes of action, minimum or no side effects …